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Human SRSF Protein Kinase 2 (SRPK2) Antibody Pair Kit | SRPK2 antibody pair kit

Human SRSF Protein Kinase 2 (SRPK2) Antibody Pair Kit (with Standard)

Gene Names
Srpk2; Wbp6; mSRPK2; AW226533; AW492537; AW547358
Reactivity
Human
Applications
ELISA, ELISA
Synonyms
SRSF Protein Kinase 2 (SRPK2); Human SRSF Protein Kinase 2 (SRPK2) Antibody Pair Kit (with Standard); SFRSK2; SFRS Protein Kinase 2; Serine/arginine-rich protein-specific kinase 2; SRPK2 antibody pair kit
Ordering
For Research Use Only!
Reactivity
Human
Applicable Applications for SRPK2 antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
Samples
Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates and Other Biological Fluids
Detection Range
31.2-2000ng/mL
Standard
Recombinant SRPK2 (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
Product Categories/Family for SRPK2 antibody pair kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
76,757 Da
NCBI Official Full Name
SRSF protein kinase 2 isoform c
NCBI Official Synonym Full Names
serine/arginine-rich protein specific kinase 2
NCBI Official Symbol
Srpk2
NCBI Official Synonym Symbols
Wbp6; mSRPK2; AW226533; AW492537; AW547358
NCBI Protein Information
SRSF protein kinase 2
UniProt Protein Name
SRSF protein kinase 2
Protein Family
UniProt Gene Name
Srpk2
UniProt Synonym Gene Names
SR-protein-specific kinase 2

Uniprot Description

Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up-regulation. Plays an essential role in spliceosomal B complex formation via the phosphorylation of DDX23/PRP28.

Research Articles on SRPK2

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Product Notes

The Human SRPK2 srpk2 (Catalog #AAA2103763) is an Antibody Pair Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2103763 Antibody Pair Kit recognizes Human SRPK2. AAA Biotech's SRSF Protein Kinase 2 (SRPK2) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex. Researchers should empirically determine the suitability of the SRPK2 srpk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SRSF Protein Kinase 2 (SRPK2), Antibody Pair Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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