FGF4 active protein

FGF4 protein

Cat. Num. AAA5304225

• Gene Names: FGF4; HST; KFGF; HST-1; HSTF1; K-FGF; HBGF-4
• Purity: FGF4 protein was purified using a a proprietary chromatographic technique.
• Synonyms: FGF4; FGF4 protein; KFGF protein; HST-1 protein; FGF 4 protein; HST protein; HBGF-4 protein; HSTF1 protein; FGF 4; K-FGF protein; FGF-4; FGF-4 protein; FGF4 active protein

• Host: Human
• Purity/Purification: FGF4 protein was purified using a a proprietary chromatographic technique.
• Form/Format: Supplied in lyophilized form from a sterile solution containing 10 mM Sodium phosphate buffer and 75 mM NaCl
• Sequence Length: 206

• Protein Type: Recombinant
• Biological Significance: Fibroblast Growth Factor 4 is a growth factor predominantly expressed during embryonic development, playing a key role in limb development. In culture, FGF4 has been shown to be an important growth factor for fibroblasts and endothelial cells.
• Bioactivity: The ED50, as determined by its ability to induce the proliferation of mouse NR6R-3T3 fibroblasts, is typically 0.025-125 ng/ml
• Endotoxin Levels: <0.01 ng/ug
• Expression System: E Coli
• Preparation and Storage: Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Related Product Information for FGF4 active protein

Purified recombinant Human FGF4 protein

Product Categories/Family for FGF4 active protein

Cytokines & Growth Factors

NCBI and Uniprot Product Information

• NCBI GI #: 4503701
• NCBI GeneID: 2249
• NCBI Accession #: NP_001998.1
• NCBI GenBank Nucleotide #: NM_002007.2
• Molecular Weight: 19 kDa
• NCBI Official Full Name: fibroblast growth factor 4
• NCBI Official Synonym Full Names: fibroblast growth factor 4
• NCBI Official Symbol: FGF4
• NCBI Official Synonym Symbols: HST; KFGF; HST-1; HSTF1; K-FGF; HBGF-4
• NCBI Protein Information: fibroblast growth factor 4
• UniProt Protein Name: Fibroblast growth factor 4
• Protein Family: Fibroblast growth factor
• UniProt Gene Name: FGF4
• UniProt Synonym Gene Names: HST; HSTF1; KS3; FGF-4; HST; HST-1; HSTF-1; HBGF-4
• UniProt Entry Name: FGF4_HUMAN

NCBI Description

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq, Jul 2008]

Uniprot Description

Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis.