Eotaxin 2 Active Protein | Ccl24 active protein
Eotaxin 2 protein
Gene Names
Ccl24; CKb-6; MPIF-2; Scya24
Applications
User optimized
Purity
> 98% pure
Synonyms
Eotaxin 2; Eotaxin 2 protein; Eotaxin-2 protein; MPIF-2 protein; CkB-6 protein; CCL24 protein; Ccl24 active protein
Host
Human
Purity/Purification
> 98% pure
Form/Format
Supplied as a lyophilized powder.
Sequence
Region of Eotaxin 2 protein corresponding to amino acids VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKGGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA.
Sequence Length
119
Applicable Applications for Ccl24 active protein
User optimized
Protein Type
Recombinant
Biological Significance
Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the Mouse homolog, without C-terminal truncation).
Bioactivity
Determined by its ability to chemoattract using human peripheral blood eosinophils using a concentration of 50.0-100.0 ng/ml.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for Ccl24 active protein
Purified recombinant Human Eotaxin 2 protein
Product Categories/Family for Ccl24 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
8.8 kDa
NCBI Official Full Name
eotaxin-2
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 24
NCBI Official Symbol
Ccl24
NCBI Official Synonym Symbols
CKb-6; MPIF-2; Scya24
NCBI Protein Information
C-C motif chemokine 24
UniProt Protein Name
C-C motif chemokine
Protein Family
UniProt Gene Name
Ccl24
UniProt Entry Name
Q3U0A4_MOUSE
Uniprot Description
CCL24: Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3. Belongs to the intercrine beta (chemokine CC) family.
Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis
Cellular Component: extracellular space; extracellular region
Molecular Function: chemokine activity; cytokine activity
Biological Process: regulation of cell shape; positive regulation of angiogenesis; positive regulation of actin filament polymerization; eosinophil chemotaxis; cytoskeleton organization and biogenesis; immune response; positive regulation of endothelial cell proliferation; chemotaxis; inflammatory response; positive regulation of cell migration; positive regulation of inflammatory response
Research Articles on Ccl24
Similar Products
Product Notes
The Ccl24 ccl24 (Catalog #AAA539601) is an Active Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Eotaxin 2 can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the Ccl24 ccl24 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Region of Eotaxin 2 protein correspond ing to amino acids VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKGGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA. It is sometimes possible for the material contained within the vial of "Eotaxin 2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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