Typical Testing Data
Human 5-hydroxytryptamine receptor 1B ELISA Kit | HTR1B elisa kit
Human 5-hydroxytryptamine receptor 1B ELISA Kit
Typical Testing Data
Typical Testing Data
Typical Standard Curve
Typical Standard Curve
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs. [provided by RefSeq, Nov 2015]
Uniprot Description
5-HT(1B): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR
Chromosomal Location of Human Ortholog: 6q13
Cellular Component: cytoplasm; integral to plasma membrane; plasma membrane
Molecular Function: drug binding; protein binding; serotonin binding; serotonin receptor activity
Biological Process: bone remodeling; drinking behavior; G-protein coupled receptor internalization; G-protein signaling, coupled to cyclic nucleotide second messenger; negative regulation of cAMP biosynthetic process; negative regulation of serotonin secretion; negative regulation of synaptic transmission, GABAergic; negative regulation of synaptic transmission, glutamatergic; protein kinase C activation; regulation of behavior; regulation of dopamine secretion; response to cocaine; response to ethanol; response to mineralocorticoid stimulus; serotonin receptor, adenylate cyclase inhibiting pathway; synaptic transmission; vasoconstriction
Research Articles on HTR1B
Similar Products
Product Notes
The Human HTR1B htr1b (Catalog #AAA763414) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA763414 ELISA Kit recognizes Human HTR1B. It is sometimes possible for the material contained within the vial of "5-hydroxytryptamine receptor 1B, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
