Western Blot (WB)
(Western Blot analysis of HuvEC cells using DGK-beta Polyclonal Antibody)
Rabbit DGKB Polyclonal Antibody | anti-DGKB antibody
DGKB Antibody
ELISA: 1:40000
Western Blot (WB)
(Western Blot analysis of HuvEC cells using DGK-beta Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of HuvEC cells using DGK-beta Polyclonal Antibody)
NCBI and Uniprot Product Information
NCBI Description
Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
DGKB: is a cytoplasmic enzyme that phosphorylates 1,2-diacylglycerol. A regulator of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD).
Protein type: Lipid Metabolism - glycerophospholipid; Kinase, lipid; Lipid Metabolism - glycerolipid; Motility/polarity/chemotaxis; EC 2.7.1.107
Chromosomal Location of Human Ortholog: 7p21.2
Cellular Component: cytoplasm; plasma membrane
Molecular Function: calcium ion binding; diacylglycerol kinase activity; ATP binding; NAD+ kinase activity
Biological Process: platelet activation; protein kinase C activation; blood coagulation; phosphorylation
Research Articles on DGKB
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Product Notes
The DGKB dgkb (Catalog #AAA7118087) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DGKB Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DGKB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000 ELISA: 1:40000. Researchers should empirically determine the suitability of the DGKB dgkb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DGKB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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