Mouse hydroxysteroid (17-beta) dehydrogenase 12 ELISA Kit | HSD17B12 elisa kit
Mouse Estradiol 17-beta-dehydrogenase 12, HSD17B12 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
HSD17B12: Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women. Also has 3-ketoacyl-CoA reductase activity, reducing both long chain 3-ketoacyl-CoAs and long chain fatty acyl-CoAs, suggesting a role in long fatty acid elongation. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
Protein type: Membrane protein, multi-pass; Lipid Metabolism - unsaturated fatty acid biosynthesis; Lipid Metabolism - androgen and estrogen; Membrane protein, integral; EC 1.1.1.62; Oxidoreductase
Cellular Component: proteinaceous extracellular matrix; membrane; endoplasmic reticulum; integral to membrane
Molecular Function: heparin binding; estradiol 17-beta-dehydrogenase activity; cis-chlorobenzene dihydrodiol dehydrogenase activity; cinnamate reductase activity; oxidoreductase activity; cis-2,3-dihydrodiol DDT dehydrogenase activity; collagen binding; 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity; trans-1,2-dihydrodiolphenanthrene dehydrogenase activity; fibronectin binding; trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity; enoyl-[acyl-carrier-protein] reductase activity; 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity
Biological Process: extracellular matrix organization and biogenesis; metabolic process; lipid metabolic process; steroid biosynthetic process
Research Articles on HSD17B12
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Product Notes
The Mouse HSD17B12 hsd17b12 (Catalog #AAA9319416) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9319416 ELISA Kit recognizes Mouse HSD17B12. It is sometimes possible for the material contained within the vial of "hydroxysteroid (17-beta) dehydrogenase 12, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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