Rat Haptoglobin ELISA Kit | Hp elisa kit
Rat Haptoglobin ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
may bind hemoglobin and mediate hemoglobin catabolism in lung cells; may play a role in inflammatory response [RGD, Feb 2006]
Uniprot Description
HP: Haptoglobin combines with free plasma hemoglobin, preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin, while making the hemoglobin accessible to degradative enzymes. Defects in HP are the cause of anhaptoglobinemia (AHP). AHP is a condition characterized by the absence of the serum glycoprotein haptoglobin. Serum levels of haptoglobin vary among normal persons: levels are low in the neonatal period and in the elderly, differ by population, and can be influenced by environmental factors, such as infection. Secondary hypohaptoglobinemia can occur as a consequence of hemolysis, during which haptoglobin binds to free hemoglobin. Belongs to the peptidase S1 family.
Protein type: Endoplasmic reticulum; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 19q12
Cellular Component: endoplasmic reticulum; extracellular space; Golgi apparatus
Molecular Function: hemoglobin binding; protein homodimerization activity
Biological Process: acute inflammatory response; aging; liver development; negative regulation of oxidoreductase activity; Notch signaling pathway; organ regeneration; response to cobalamin; response to drug; response to electrical stimulus; response to glucocorticoid stimulus; response to heat; response to hydrogen peroxide; response to hypoxia; response to L-ascorbic acid; response to lead ion; response to lipopolysaccharide; response to magnesium ion; response to organic cyclic substance; response to organic substance; response to starvation; response to X-ray; spermatogenesis
Research Articles on Hp
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Product Notes
The Rat Hp hp (Catalog #AAA9426128) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9426128 ELISA Kit recognizes Rat Hp. It is sometimes possible for the material contained within the vial of "Haptoglobin, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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