Human histidine acid phosphatase domain containing 1 ELISA Kit | HISPPD1 elisa kit
Human Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2, HISPPD1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively (Fridy et al., 2007 [PubMed 17690096]).[supplied by OMIM, Mar 2008]
Uniprot Description
PPIP5K2: a multifunctional enzyme with inositol kinase activity. Catalyzes the formation of diphosphoinositol pentakisphosphate (PP-InsP5) and bi-diphosphoinositol tetrakisphosphate (PP2- InsP4). Converts inositol hexakisphosphate (InsP6) to InsP7. Also able to convert InsP7 to InsP8. Mediates the formation of 1PP-InsP5. Belongs to the histidine acid phosphatase family. VIP1 subfamily. The His_Phos_2 domain has no apparent phosphatase activity but has been shown to have cryptic polyphosphoinositide binding activity. Two isoforms of the human protein are produced by alternative splicing. Note: This description may include information
Protein type: EC 2.7.4.24; Kinase, lipid; EC 2.7.4.21
Chromosomal Location of Human Ortholog: 5q21.1
Cellular Component: cytosol
Molecular Function: inositol 1,3,4,5,6-pentakisphosphate kinase activity; acid phosphatase activity; inositol hexakisphosphate 5-kinase activity; ATP binding; diphosphoinositol-pentakisphosphate kinase activity
Biological Process: inositol phosphate metabolic process; dephosphorylation; inositol metabolic process; phosphorylation
Research Articles on HISPPD1
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Product Notes
The Human HISPPD1 ppip5k2 (Catalog #AAA9319302) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9319302 ELISA Kit recognizes Human HISPPD1. It is sometimes possible for the material contained within the vial of "histidine acid phosphatase domain containing 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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