Human helicase (DNA) B ELISA Kit | HELB elisa kit
Human DNA helicase B, HELB ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a DNA-dependent ATPase which catalyzes the unwinding of DNA necessary for DNA replication, repair, recombination, and transcription. This gene is thought to function specifically during the S phase entry of the cell cycle. [provided by RefSeq, Mar 2012]
Uniprot Description
helicase B: Unwinds duplex DNA with 5'-3' polarity. Has single- strand DNA-dependent ATPase and DNA helicase activities. Prefers ATP and dATP as substrates. During S phase, may facilitate cellular recovery from replication stress. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.6.4.12; DNA replication; Helicase
Chromosomal Location of Human Ortholog: 12q14.3|12q
Cellular Component: alpha DNA polymerase:primase complex; cytoplasm
Molecular Function: ATP-dependent 5'-3' DNA helicase activity; single-stranded DNA-dependent ATP-dependent DNA helicase activity; ATP binding; ATP-dependent RNA helicase activity
Biological Process: RNA processing; DNA replication, synthesis of RNA primer; DNA replication; DNA duplex unwinding
Research Articles on HELB
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Product Notes
The Human HELB helb (Catalog #AAA9336051) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9336051 ELISA Kit recognizes Human HELB. It is sometimes possible for the material contained within the vial of "helicase (DNA) B, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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