SDS-Page
B7-1/CD80, Cynomolgus Active Protein | TNFSF10 active protein
Human CellExp B7-1/CD80, Cynomolgus Recombinant
Purity
>=95% by SDS-PAGE; >=90% by HPLC
Synonyms
B7-1/CD80; Cynomolgus; Human CellExp B7-1/CD80; Cynomolgus Recombinant; Apo-2L; TRAIL; CD253; TNFSF10; Apo-2 ligand; TNFSF10 active protein
Host
HEK293 cells
Purity/Purification
>=95% by SDS-PAGE; >=90% by HPLC
Form/Format
Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Gene Source
Cynomolgus
Endotoxin
Less than 1.0 EU per ug by the LAL method.
Biological Activity
This protein carries a mouse IgG2a Fc tag at the N-terminus.
Reconstitution Instruction
Reconstitute in sterile deionized water to the desired protein concentration.
Tag Note
This protein carries a mouse IgG2a Fc tag at the N-terminus.
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Centrifuge the vial prior to opening.
Shelf life: ~12 months
SDS-Page
SDS-Page
Testing Data
Testing Data
Related Product Information for TNFSF10 active protein
TRAIL, also known as TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL, TNLG6A and TNF superfamily member 10. The TRAIL gene as a drug target, induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. TRAIL also binds the receptors DcR1 and DcR2, which do not contain a cytoplasmic domain (DcR1) or contain a truncated death domain (DcR2). DcR1 functions as a TRAIL-neutralizing decoy-receptor. The cytoplasmic domain of DcR2 is functional and activates NFkappaB. In cells expressing DcR2, TRAIL binding therefore activates NFkappaB, leading to transcription of genes known to antagonize the death signaling pathway and/or to promote inflammation. Plays a role in induction of innate immune responses by activating NF-kappaB-signaling pathway in macrophages
Product Categories/Family for TNFSF10 active protein
NCBI and Uniprot Product Information
NCBI GeneID
UniProt Accession #
Molecular Weight
Calculated MW of 46.4kDa.
The protein migrates as 47-55kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
The protein migrates as 47-55kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein Family
Similar Products
Product Notes
The TNFSF10 (Catalog #AAA849887) is an Active Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "B7-1/CD80, Cynomolgus, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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