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MAG/Siglec-4a Recombinant Protein | MAG recombinant protein
Human CellExp MAG/Siglec-4a, Fc Tag, Human Recombinant
Purity
>95% by SDS-PAGE
Synonyms
MAG/Siglec-4a; Human CellExp MAG/Siglec-4a; Fc Tag; Human Recombinant; MAG; Siglec-4a; GMA; S-MAG; MAG recombinant protein
Host
HEK293 cells
Purity/Purification
>95% by SDS-PAGE
Form/Format
Lyophilized powder. Lyophilized from 0.22um filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization
Sequence
Gly20-Pro516
Gene Source
Human
Endotoxin
Less than 1.0 EU per ug by the LAL method.
Reconstitution Instruction
Reconstitute in sterile deionized water to the desired protein concentration.
Tag Note
This protein carries a human IgG1 Fc tag at the C-terminus.
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Centrifuge the vial prior to opening.
Shelf life: ~12 months
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Related Product Information for MAG recombinant protein
Myelin-associated glycoprotein (MAG), a nervous system cell adhesion molecule, is an I-type lectin that binds to sialylated glycoconjugates, including gangliosides bearing characteristic structural determinants. Preferentially binds to alpha-2,3-linked sialic acid. Binds ganglioside Gt1b. Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2. Protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2. In dorsal root ganglion neurons the inhibition is mediated primarily via binding to neuronal RTN4R or RTN4RL2 and to a lesser degree via binding to neuronal gangliosides. In cerebellar granule cells the inhibition is mediated primarily via binding to neuronal gangliosides. In sensory neurons, inhibition of neurite extension depends only partially on RTN4R, RTN4RL2 and gangliosides.
Product Categories/Family for MAG recombinant protein
NCBI and Uniprot Product Information
NCBI GeneID
UniProt Accession #
Molecular Weight
Calculated MW of 81.1kDa.
The protein migrates as 100-115kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
The protein migrates as 100-115kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein Family
Similar Products
Product Notes
The MAG (Catalog #AAA8400104) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Gly20-Pro5 16. It is sometimes possible for the material contained within the vial of "MAG/Siglec-4a, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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