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Dll1 active protein

Human CellExp DLL1, Mouse Recombinant

Gene Names
Dll1; Delta1
Purity
>90% by SDS-PAGE
Synonyms
DLL1; Human CellExp DLL1; Mouse Recombinant; Delta-like Protein 1; Delta 1; Dll1 active protein
Ordering
For Research Use Only!
Host
HEK293 cells
Purity/Purification
>90% by SDS-PAGE
Form/Format
Lyophilized powder. Lyophilized from 0.2 um-filtered PBS
Gene Source
Mouse
Endotoxin
<1.0 EU per/ug
Biological Activity
Measured by inhibition of adipogenesis of 3T3L-1 cells and induction of Hes-1 in 3T3L-1 cells
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months

SDS-Page

SDS-Page
Related Product Information for Dll1 active protein
The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
78,449 Da
NCBI Official Full Name
delta-like protein 1
NCBI Official Synonym Full Names
delta-like 1 (Drosophila)
NCBI Official Symbol
Dll1
NCBI Official Synonym Symbols
Delta1
NCBI Protein Information
delta-like protein 1; delta like-1; drosophila Delta homolog 1
UniProt Protein Name
Delta-like protein 1
Protein Family
UniProt Gene Name
Dll1
UniProt Synonym Gene Names
Delta1
UniProt Entry Name
DLL1_MOUSE

Uniprot Description

DLL1: Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. Interacts with Notch receptors. Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.

Protein type: Cell development/differentiation; Membrane protein, integral; Motility/polarity/chemotaxis

Cellular Component: membrane; plasma membrane; integral to membrane; cytoplasmic vesicle

Molecular Function: protein binding; calcium ion binding; Notch binding

Biological Process: nervous system development; somitogenesis; Notch signaling pathway; inner ear morphogenesis; negative regulation of myeloid cell differentiation; negative regulation of interleukin-10 production; in utero embryonic development; multicellular organismal development; auditory receptor cell differentiation; odontogenesis of dentine-containing teeth; compartment specification; negative regulation of cell differentiation; somite specification; organ morphogenesis; negative regulation of neuron differentiation; regulation of neurogenesis; cell-cell signaling; negative regulation of auditory receptor cell differentiation; positive regulation of transcription from RNA polymerase II promoter; cell communication; heart looping; determination of left/right symmetry; cell differentiation; auditory receptor cell fate commitment; inner ear development; positive regulation of Notch signaling pathway

Research Articles on Dll1

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Product Notes

The Dll1 dll1 (Catalog #AAA849790) is an Active Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "DLL1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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