Hemagglutinin-esterase (HE) Recombinant Protein | HE recombinant protein
Recombinant Puffinosis coronavirus Hemagglutinin-esterase (HE)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
Uniprot Description
Structural protein that makes short spikes at the surface of the virus. Contains receptor binding and receptor-destroying activities. Mediates de-O-acetylation of N-acetyl-4-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells. This receptor-destroying activity is important for virus release as it probably helps preventing self-aggregation and ensures the efficient spread of the progeny virus from cell to cell. May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one. Seems to be a 'luxury' protein that is not absolutely necessary for virus infection in culture. However, its presence in the virus may alter its pathogenicity. May become a target for both the humoral and the cellular branches of the immune system.
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Product Notes
The HE he (Catalog #AAA7016571) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 25-439aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the HE he for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: FNEPLNVVSH LSDDWFLFGD SRSDCSYVEN NGHPAFDWLD LPQELCHSGK ISAKSGNSLF KSFHFTDWYN YTGEGDQVIF YEGVNFSPSH GFKCLAEGDN KRWMGNKARF YALVYKKMAY YRSLSFVNVS YSYGGKAKPT AICKDNTLTL NNPTFISKES NYVDYYYESD ANFTLEGCDE FIVPLCVFNG HSRGSSSDPA NKYYMDSQMY YNMDTGVFYG FNSTLDVGNT AQNPGLDLTC IYYALTPGNY KAVSLEYLLT IPSKAICLRK PKRFMPVQVV DSRWNNAKHS DNMTAVACQT PYCLFRNTSS GYNGSTHDVH HGGFHFRKLL SGLLYNVSCI AQQGAFFYNN VSSQWPVLGY GQCPTAANIE FIAPVCLYDP LPVILLGVLL GIAVLIIVFL LFYFMTDSGV RLHEA. It is sometimes possible for the material contained within the vial of "Hemagglutinin-esterase (HE), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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