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Hamster Na+/H+ Exchange Regulatory Cofactor NHE-RF1 (SLC9A3R1) ELISA Kit | SLC9A3R1 elisa kit

Hamster Na+/H+ Exchange Regulatory Cofactor NHE-RF1 (SLC9A3R1) ELISA Kit

Gene Names
SLC9A3R1; EBP50; NHERF; NHERF1; NHERF-1; NPHLOP2
Reactivity
Hamster
Synonyms
Na+/H+ Exchange Regulatory Cofactor NHE-RF1 (SLC9A3R1); Hamster Na+/H+ Exchange Regulatory Cofactor NHE-RF1 (SLC9A3R1) ELISA Kit; SLC9A3R1 elisa kit
Ordering
For Research Use Only!
Reactivity
Hamster
Preparation and Storage
Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22,034 Da
NCBI Official Full Name
Na(+)/H(+) exchange regulatory cofactor NHE-RF1
NCBI Official Synonym Full Names
SLC9A3 regulator 1
NCBI Official Symbol
SLC9A3R1
NCBI Official Synonym Symbols
EBP50; NHERF; NHERF1; NHERF-1; NPHLOP2
NCBI Protein Information
Na(+)/H(+) exchange regulatory cofactor NHE-RF1
UniProt Protein Name
Na(+)/H(+) exchange regulatory cofactor NHE-RF1
UniProt Gene Name
SLC9A3R1
UniProt Synonym Gene Names
NHERF; NHERF1; NHERF-1; EBP50
UniProt Entry Name
NHRF1_HUMAN

NCBI Description

This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009]

Uniprot Description

Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli (). Involved in the regulation of phosphate reabsorption in the renal proximal tubules. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa.

Research Articles on SLC9A3R1

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Product Notes

The Hamster SLC9A3R1 slc9a3r1 (Catalog #AAA9363190) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9363190 ELISA Kit recognizes Hamster SLC9A3R1. It is sometimes possible for the material contained within the vial of "Na+/H+ Exchange Regulatory Cofactor NHE-RF1 (SLC9A3R1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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