Hamster Elongation Factor Tu, Mitochondrial (TUFM) ELISA Kit | TUFM elisa kit
Hamster Elongation Factor Tu, Mitochondrial (TUFM) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2008]
Uniprot Description
EFTU: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Defects in TUFM are the cause of combined oxidative phosphorylation deficiency type 4 (COXPD4). COXPD4 is characterized by neonatal lactic acidosis, rapidly progressive encephalopathy, severely decreased mitochondrial protein synthesis, and combined deficiency of mtDNA-related mitochondrial respiratory chain complexes. Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.
Protein type: Mitochondrial; RNA-binding; Translation; Translation elongation
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: membrane; mitochondrion
Molecular Function: GTPase activity; protein binding; translation elongation factor activity
Biological Process: translational elongation
Disease: Combined Oxidative Phosphorylation Deficiency 4
Research Articles on TUFM
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Product Notes
The Hamster TUFM tufm (Catalog #AAA9395447) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9395447 ELISA Kit recognizes Hamster TUFM. It is sometimes possible for the material contained within the vial of "Elongation Factor Tu, Mitochondrial (TUFM), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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