Hyaluronan-Binding Protein 2/HABP2 Recombinant Protein | HABP2 recombinant protein
Recombinant Human Hyaluronan-Binding Protein 2/HABP2 Protein (C-6His)
Purity
>90% as determined by SDS-PAGE
Synonyms
Hyaluronan-Binding Protein 2/HABP2; Recombinant Human Hyaluronan-Binding Protein 2/HABP2 Protein (C-6His); Hyaluronan-binding protein 2; Factor VII-activating protease; Factor seven-activating protease; Hepatocyte growth factor activator-like protein; Plasma hyaluronan-binding protein; HABP2 recombinant protein
Host
Human Cells
Purity/Purification
>90% as determined by SDS-PAGE
Form/Format
Lyophilized from a 0.2 mum filtered solution of PBS, pH7.4.
Sequence
Met1-Gln279
Sequence Length
534
Species
Human
Endotoxin
< 1.0 EU per mug as determined by the LAL method.
Fusion Tag
C-6His
Preparation and Storage
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80 degree C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Related Product Information for HABP2 recombinant protein
Protein Construction: Recombinant Human Hyaluronan-binding Protein 2 is produced by our mammalian expression system and the target gene encoding Met1-Gln279 is expressed with a 6His tag at the C-terminus.
Background: Hyaluronan-binding protein 2(HABP2) is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond. HABP2 is involved in cell adhesion, it can cleave the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54', but not the gamma-chain of fibrinogen. As a result of this, it does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator to the active two chain form, activates coagulation factor VII.
Background: Hyaluronan-binding protein 2(HABP2) is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond. HABP2 is involved in cell adhesion, it can cleave the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54', but not the gamma-chain of fibrinogen. As a result of this, it does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator to the active two chain form, activates coagulation factor VII.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 36.2kDa
Actual Protein Molecular Mass: 38kDa
Actual Protein Molecular Mass: 38kDa
NCBI Official Full Name
hyaluronan-binding protein 2 isoform 2
UniProt Protein Name
Hyaluronan-binding protein 2
Protein Family
UniProt Gene Name
HABP2
UniProt Synonym Gene Names
HGFAL; PHBP; FSAP
UniProt Entry Name
HABP2_HUMAN
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Product Notes
The HABP2 habp2 (Catalog #AAA2557078) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Gln27 9. It is sometimes possible for the material contained within the vial of "Hyaluronan-Binding Protein 2/HABP2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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