Guinea Pig Vacuolar protein sorting-associated protein 29 (VPS29) ELISA Kit | VPS29 elisa kit
Guinea pig Vacuolar protein sorting-associated protein 29 (VPS29) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms and representing non-protein coding transcripts have been found for this gene. [provided by RefSeq, Aug 2013]
Uniprot Description
VPS29: Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro). Belongs to the VPS29 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.3.3; Vesicle; Protein phosphatase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 12q24
Cellular Component: intracellular membrane-bound organelle; retromer complex; early endosome; cytoplasm; late endosome; endosome membrane; cytosol; endosome
Molecular Function: protein binding; zinc ion binding; protein transporter activity
Biological Process: intracellular protein transport; retrograde transport, endosome to Golgi
Research Articles on VPS29
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Product Notes
The Guinea Pig VPS29 vps29 (Catalog #AAA7236419) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7236419 ELISA Kit recognizes Guinea Pig VPS29. It is sometimes possible for the material contained within the vial of "Vacuolar protein sorting-associated protein 29 (VPS29), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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