Guinea Pig Protein maelstrom homolog (MAEL) ELISA Kit | MAEL elisa kit
Guinea pig Protein maelstrom homolog (MAEL) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
MAEL: Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage. Belongs to the maelstrom family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: 1q24.1
Cellular Component: XY body; autosome; perinuclear region of cytoplasm; cytoplasm; chromatin; nucleus
Molecular Function: DNA binding
Biological Process: multicellular organismal development; DNA methylation during gametogenesis; cell morphogenesis; regulation of organ growth; negative regulation of transcription from RNA polymerase II promoter; male meiosis; fertilization; DNA damage response, signal transduction resulting in induction of apoptosis; synapsis; RNA-mediated gene silencing; gene expression; spermatogenesis; cell differentiation; negative regulation of apoptosis
Research Articles on MAEL
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Product Notes
The Guinea Pig MAEL mael (Catalog #AAA7233097) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7233097 ELISA Kit recognizes Guinea Pig MAEL. It is sometimes possible for the material contained within the vial of "Protein maelstrom homolog (MAEL), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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