Guinea Pig Pituitary-specific positive transcription factor 1 (POU1F1) ELISA Kit | POU1F1 elisa kit
Guinea pig Pituitary-specific positive transcription factor 1 (POU1F1) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
GHF-1: Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'- TAAAT-3'. Belongs to the POU transcription factor family. Class- 1 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 3p11
Cellular Component: nucleoplasm; cytoplasm
Molecular Function: chromatin binding; transcription corepressor activity; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; nuclear transport; regulation of insulin-like growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of inositol trisphosphate biosynthetic process; cell fate specification; determination of adult life span; positive regulation of multicellular organism growth; negative regulation of transcription from RNA polymerase II promoter; negative regulation of cell proliferation; regulation of transcription, DNA-dependent; B cell differentiation; positive regulation of cell proliferation; somatotropin secreting cell development; positive regulation of transcription from RNA polymerase II promoter
Disease: Pituitary Hormone Deficiency, Combined, 1
Research Articles on POU1F1
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Product Notes
The Guinea Pig POU1F1 pou1f1 (Catalog #AAA7206589) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7206589 ELISA Kit recognizes Guinea Pig POU1F1. It is sometimes possible for the material contained within the vial of "Pituitary-specific positive transcription factor 1 (POU1F1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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