Guinea Pig CHRNA7-FAM7A fusion protein (CHRFAM7A) ELISA Kit | CHRFAM7A elisa kit
Guinea pig CHRNA7-FAM7A fusion protein (CHRFAM7A) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008]
Uniprot Description
CHRFAM7A: Belongs to the ligand-gated ion channel (TC 1.A.9) family
Protein type: Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 15q13.1
Cellular Component: integral to membrane
Molecular Function: extracellular ligand-gated ion channel activity
Research Articles on CHRFAM7A
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Product Notes
The Guinea Pig CHRFAM7A chrfam7a (Catalog #AAA7206512) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7206512 ELISA Kit recognizes Guinea Pig CHRFAM7A. It is sometimes possible for the material contained within the vial of "CHRNA7-FAM7A fusion protein (CHRFAM7A), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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