Guinea Pig Carbonic anhydrase-related protein (CA8) ELISA Kit | CA8 elisa kit
Guinea pig Carbonic anhydrase-related protein (CA8) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. [provided by RefSeq, Jul 2008]
Uniprot Description
CA8: Does not have a carbonic anhydrase catalytic activity. Defects in CA8 are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 3 (CMARQ3). CMARQ3 is a congenital cerebellar ataxia associated with dysarthia, quadrupedal gait and mild mental retardation. Belongs to the alpha-carbonic anhydrase family.
Protein type: Energy Metabolism - nitrogen; Lyase
Chromosomal Location of Human Ortholog: 8q12.1
Cellular Component: cytoplasm
Molecular Function: carbonate dehydratase activity; zinc ion binding
Biological Process: phosphoinositide-mediated signaling; one-carbon compound metabolic process
Disease: Cerebellar Ataxia, Mental Retardation, And Dysequilibrium Syndrome 3
Research Articles on CA8
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Product Notes
The Guinea Pig CA8 ca8 (Catalog #AAA7218412) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7218412 ELISA Kit recognizes Guinea Pig CA8. It is sometimes possible for the material contained within the vial of "Carbonic anhydrase-related protein (CA8), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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