Guinea Pig ADAMTS-like protein 4 (ADAMTSL4) ELISA Kit | ADAMTSL4 elisa kit
Guinea pig ADAMTS-like protein 4 (ADAMTSL4) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Sep 2014]
Uniprot Description
TSRC1: Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis. Defects in ADAMTSL4 are a cause of autosomal recessive isolated ectopia lentis (ARI-EL). ARI-EL is a rare condition characterized by partial or complete displacement of the lens from its space resulting from defective zonule formation. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1q21.3
Cellular Component: endoplasmic reticulum lumen
Molecular Function: protein binding; protease binding; metalloendopeptidase activity
Biological Process: protein amino acid O-linked glycosylation; extracellular matrix organization and biogenesis; cellular protein metabolic process; apoptosis; positive regulation of apoptosis; post-translational protein modification; proteolysis
Disease: Ectopia Lentis Et Pupillae; Ectopia Lentis 2, Isolated, Autosomal Recessive
Research Articles on ADAMTSL4
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Product Notes
The Guinea Pig ADAMTSL4 adamtsl4 (Catalog #AAA7251161) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7251161 ELISA Kit recognizes Guinea Pig ADAMTSL4. It is sometimes possible for the material contained within the vial of "ADAMTS-like protein 4 (ADAMTSL4), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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