Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) Recombinant Protein | GPIHBP1 recombinant protein
Recombinant Human Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a capillary endothelial cell protein that facilitates the lipolytic processing of triglyceride-rich lipoproteins. The encoded protein is a glycosylphosphatidylinositol-anchored protein that is a member of the lymphocyte antigen 6 (Ly6) family. This protein plays a major role in transporting lipoprotein lipase (LPL) from the subendothelial spaces to the capillary lumen. Mutations in this gene are the cause of hyperlipoproteinemia, type 1D. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Uniprot Description
GPIHBP1: Plays a key role in the lipolytic processing of chylomicrons.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: anchored to external side of plasma membrane; apical plasma membrane; basolateral plasma membrane; external side of plasma membrane; intracellular
Molecular Function: high-density lipoprotein binding; lipid binding; protein transmembrane transporter activity
Biological Process: cholesterol homeostasis; intracellular protein transport; lipid transport; positive regulation of lipoprotein lipase activity; protein import; protein stabilization; transcytosis
Disease: Hyperlipoproteinemia, Type Id
Research Articles on GPIHBP1
Similar Products
Product Notes
The GPIHBP1 gpihbp1 (Catalog #AAA7016041) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 21-184aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the GPIHBP1 gpihbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: QTQQEEEEED EDHGPDDYDE EDEDEVEEEE TNRLPGGRSR VLLRCYTCKS LPRDERCNLT QNCSHGQTCT TLIAHGNTES GLLTTHSTWC TDSCQPITKT VEGTQVTMTC CQSSLCNVPP WQSSRVQDPT GKGAGGPRGS SETVGAALLL NLLAGLGAMG ARRP. It is sometimes possible for the material contained within the vial of "Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
