Goat Adenosine deaminase CECR1 (CECR1) ELISA Kit | CECR1 elisa kit
Goat Adenosine deaminase CECR1 (CECR1) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a subfamily of the adenosine deaminase protein family. The encoded protein is one of two adenosine deaminases found in humans, which regulate levels of the signaling molecule, adenosine. The encoded protein is secreted from monocytes undergoing differentiation and may regulate cell proliferation and differentiation. This gene may be responsible for some of the phenotypic features associated with cat eye syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Uniprot Description
CECR1: Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity. Belongs to the adenosine and AMP deaminases family. ADGF subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Hydrolase; Secreted, signal peptide; EC 3.5.4.4
Chromosomal Location of Human Ortholog: 22q11.2
Cellular Component: extracellular space; cytosol
Molecular Function: adenosine deaminase activity; heparin binding; proteoglycan binding; protein homodimerization activity; growth factor activity; zinc ion binding; adenosine receptor binding
Biological Process: adenosine catabolic process; multicellular organismal development; hypoxanthine salvage; inosine biosynthetic process
Disease: Polyarteritis Nodosa, Childhood-onset; Sneddon Syndrome