Immunohistochemistry (IHC)
(Immunochemical staining of mouse NAALADL1 in mouse brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Rabbit anti-Mouse NAALADL1 Polyclonal Antibody | anti-NAALADL1 antibody
Anti-NAALADL1 Antibody, Rabbit Polyclonal
Gene Names
Naaladl1; Gm964; Naaladasel
Reactivity
Mouse
Applications
ELISA, Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
NAALADL1; Polyclonal Antibody; Anti-NAALADL1 Antibody; Rabbit Polyclonal; NAALADL1 Antibody; Rabbit PAb; Antigen Affinity Purified; N-acetylated alpha-linked acidic dipeptidase-like 1; Anti-Gm964 Antibody; Anti-Naaladasel Antibody; anti-NAALADL1 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Mouse NAALADL1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-NAALADL1 antibody
ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
ELISA: 1:5000-1:10,000
IHC-P: 1:500-1:2000
IHC-P: 1:500-1:2000
Immunogen
Recombinant Mouse NAALADL1 protein
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with purified, recombinant Mouse NAALADL1 (rM NAALADL1). NAALADL1 specific IgG was purified by Mouse NAALADL1 affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of mouse NAALADL1 in mouse brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining of mouse NAALADL1 in mouse brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Related Product Information for anti-NAALADL1 antibody
N-acetylated-alpha-linked acidic dipeptidase-like protein, also known as NAALADL1, NAALADase L, and Ileal dipeptidyl-peptidase, is a Single-pass type II membrane protein and a member of the peptidase M28 family and M28B subfamily. NAALADase L is mainly expressed in the distal small intestine. It is also expressed in the spleen and testis and Weakly expressed in the brain, locating mainly to the brain stem, amygdala, thalamus, and ventral striatum. NAALADase L is a chloride-activated, membrane-bound, metallopeptidase that cleaves the endogenous neuropeptide N-acetyl-aspartyl-glutamate (NAAG). NAAG acts as a partial NMDA agonist as well as a full agonist at the presynaptic metabotropic glutamate receptor 3 (mGluR3), where it acts to reduce glutamate release. NAALADase L also exhibits a dipeptidyl-peptidase IV type activity. NAALADase inhibition may be a novel therapeutic approach to reduce or inhibit heightened aggressiveness, and possibly to treat aggressive behavior associated with psychiatric disorders.
References
Stauch BL. 1989, Neurosci Lett. 100 (1-3): 295-300. Shneider BL. et al., 1997, J. Biol. Chem. 272: 31006-15. Pangalos MN. et al., 1999, J. Biol. Chem. 274: 8470-83. Thomas AG. et al., 1999, Brain Res. 843 (1-2): 48-52.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
80,513 Da
NCBI Official Full Name
N-acetylated-alpha-linked acidic dipeptidase-like protein
NCBI Official Synonym Full Names
N-acetylated alpha-linked acidic dipeptidase-like 1
NCBI Official Symbol
Naaladl1
NCBI Official Synonym Symbols
Gm964; Naaladasel
NCBI Protein Information
N-acetylated-alpha-linked acidic dipeptidase-like protein; NAALADase L; N-acetylated-alpha-linked acidic dipeptidase like protein
UniProt Protein Name
N-acetylated-alpha-linked acidic dipeptidase-like protein
Protein Family
UniProt Gene Name
Naaladl1
UniProt Synonym Gene Names
Gm964; Naaladasel; NAALADase L
UniProt Entry Name
NALDL_MOUSE
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Product Notes
The NAALADL1 naaladl1 (Catalog #AAA8112175) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-NAALADL1 Antibody, Rabbit Polyclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NAALADL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P). ELISA: 1:5000-1:10,000 IHC-P: 1:500-1:2000. Researchers should empirically determine the suitability of the NAALADL1 naaladl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NAALADL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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