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Progonadoliberin-2/GNRH2 Recombinant Protein | GNRH2 recombinant protein

Recombinant Human Progonadoliberin-2/GNRH2 Protein (C-6His)

Gene Names
GNRH2; GnRH-II; LH-RHII
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Progonadoliberin-2/GNRH2; Recombinant Human Progonadoliberin-2/GNRH2 Protein (C-6His); Progonadoliberin-2; Progonadoliberin II; Gonadoliberin-2; Gonadoliberin II; Gonadotropin-Releasing Hormone II; GnRH II; Luliberin II; Luteinizing Hormone-Releasing Hormone II; LH-RH II; GnRH-Associated Peptide 2; GnRH-Associated Peptide II; GNRH2; GNRH2 recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of PBS, pH 7.4.
Sequence Positions
Gln24-Val120
Sequence Length
120
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fusion Tag
C-6His
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Related Product Information for GNRH2 recombinant protein
Progonadoliberin-2, also known as Progonadoliberin II and GNRH2, belongs to the gonadotropin-releasing hormone family. GNRH2 is specially expressed in midbrain, at significantly higher levels outside the brain (up to 30-fold). GNRH2 can be cleaved into two chains, gonadoliberin-2 and GnRH-associated peptide 2. gonadoliberin-2 regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones. The proproteins produce three transcript variants, but produce the same peptide hormone.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 11.5 kDa
Actual Protein Molecular Mass: 15-20 kDa
NCBI Official Full Name
progonadoliberin-2 isoform a preproprotein
NCBI Official Synonym Full Names
gonadotropin releasing hormone 2
NCBI Official Symbol
GNRH2
NCBI Official Synonym Symbols
GnRH-II; LH-RHII
NCBI Protein Information
progonadoliberin-2
UniProt Protein Name
Progonadoliberin-2
Protein Family
UniProt Gene Name
GNRH2
UniProt Synonym Gene Names
GnRH II; LH-RH II

NCBI Description

This gene encodes a secreted peptide hormone and member of the gonadotropin-releasing hormone (GnRH) family of proteins. The encoded protein regulates reproductive function by stimulating the production and release of the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The encoded protein may inhibit endometrial, ovarian, prostate, and breast cancer cell proliferation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

Uniprot Description

Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.

Research Articles on GNRH2

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Product Notes

The GNRH2 gnrh2 (Catalog #AAA2553127) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Gln24-Val120. It is sometimes possible for the material contained within the vial of "Progonadoliberin-2/GNRH2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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