NCBI and Uniprot Product Information
NCBI Description
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Uniprot Description
G-beta 1: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the WD repeat G protein beta family.
Protein type: G protein; G protein, heterotrimeric beta; G protein, heterotrimeric
Chromosomal Location of Human Ortholog: 1p36.33
Cellular Component: photoreceptor inner segment; membrane; lysosomal membrane; dendrite; plasma membrane; heterotrimeric G-protein complex; intracellular; vesicle
Molecular Function: GTPase activity; signal transducer activity; protein binding; GTPase binding; spectrin binding; protein complex binding; type 1 angiotensin receptor binding
Biological Process: phototransduction, visible light; platelet activation; acetylcholine receptor signaling, muscarinic pathway; sensory perception of taste; signal transduction; rhodopsin mediated signaling; cell proliferation; synaptic transmission; elevation of cytosolic calcium ion concentration; regulation of rhodopsin mediated signaling; retina development in camera-type eye; Ras protein signal transduction; energy reserve metabolic process; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); blood coagulation; dopamine receptor, adenylate cyclase activating pathway
Research Articles on GNb1
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Product Notes
The Mouse GNb1 gnb1 (Catalog #AAA722204) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA722204 ELISA Kit recognizes Mouse GNb1. It is sometimes possible for the material contained within the vial of "G Protein Beta 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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