Human guanine nucleotide binding protein (G protein) alpha 12 ELISA Kit | GNA12 elisa kit

Human Guanine nucleotide-binding protein subunit alpha-12, GNA12 ELISA Kit

Cat. Num. AAA9317428

• Gene Names: GNA12; RMP; gep; NNX3
• Reactivity: Human
• Synonyms: guanine nucleotide binding protein (G protein) alpha 12; Human Guanine nucleotide-binding protein subunit alpha-12; GNA12 ELISA Kit; Human Guanine nucleotide-binding protein subunit alpha-12 (GNA12) ELISA kit; MGC104623; MGC99644; NNX3; RMP; gep; WUGSC:H_GS165O14.2; GNA12 elisa kit

• Reactivity: Human

• Assay Type: Quantitative Sandwich
• Detection Range: 0.625ng/ml-20ng/ml
• Sensitivity: 0.1ng/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for GNA12 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of GNA12 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

References

Bone Homeostasis as a Multifaceted Puzzle: From WNT Ligands to Metal-ion Transporters. G. Hendrickx (2017)

NCBI and Uniprot Product Information

• NCBI GI #: 540344584
• NCBI GeneID: 2768
• NCBI Accession #: NP_001269370.1
• NCBI GenBank Nucleotide #: NM_001282441.1
• UniProt Accession #: Q03113; Q2T9L1; Q5PPR5; Q86UM8; Q8TD71; Q9UDU9; A4D204; B3KXS2; B7Z3F7
• Molecular Weight: 44,279 Da
• NCBI Official Full Name: guanine nucleotide-binding protein subunit alpha-12 isoform 3
• NCBI Official Synonym Full Names: guanine nucleotide binding protein (G protein) alpha 12
• NCBI Official Symbol: GNA12
• NCBI Official Synonym Symbols: RMP; gep; NNX3
• NCBI Protein Information: guanine nucleotide-binding protein subunit alpha-12; g alpha-12; WUGSC:H_GS165O14.2; G-protein subunit alpha-12
• UniProt Protein Name: Guanine nucleotide-binding protein subunit alpha-12
• Protein Family: Guanine nucleotide-binding protein
• UniProt Gene Name: GNA12
• UniProt Synonym Gene Names: G alpha-12; G-protein subunit alpha-12
• UniProt Entry Name: GNA12_HUMAN

Uniprot Description

G-alpha 12: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Belongs to the G-alpha family. G(12) subfamily.

Protein type: G protein, heterotrimeric alpha G(12); G protein, heterotrimeric; G protein

Chromosomal Location of Human Ortholog: 7p22.2

Cellular Component: focal adhesion; brush border membrane; plasma membrane; heterotrimeric G-protein complex

Molecular Function: GTPase activity; protein binding; signal transducer activity; GTP binding; metal ion binding; G-protein beta/gamma-subunit binding; D5 dopamine receptor binding

Biological Process: response to drug; G-protein signaling, coupled to cAMP nucleotide second messenger; platelet activation; regulation of cell shape; G-protein coupled receptor protein signaling pathway; metabolic process; in utero embryonic development; regulation of proteasomal ubiquitin-dependent protein catabolic process; embryonic digit morphogenesis; blood coagulation; cell differentiation; Rho protein signal transduction; regulation of TOR signaling pathway