Guanosine Monophosphate Reductase Recombinant Protein | GMPR recombinant protein
Recombinant Human Guanosine Monophosphate Reductase
Gene Names
GMPR; GMPR1
Purity
Greater than 95.0% as determined by SDS-PAGE.
Synonyms
Guanosine Monophosphate Reductase; Recombinant Human Guanosine Monophosphate Reductase; GMPR Human; Guanosine Monophosphate Reductase Human Recombinant; GMP reductase 1; Guanosine 5'-monophosphate oxidoreductase 1; Guanosine monophosphate reductase 1; GMPR; GMPR1; GMPR recombinant protein
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
The GMPR solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 40% glycerol, 0.15M NaCl and 1mM DTT.
Sterile Filtered clear colorless solution.
Sterile Filtered clear colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MPRIDADLKL DFKDVLLRPK RSSLKSRAEV DLERTFTFRN SKQTYSGIPI IVANMDTVGT FEMAAVMSQH SMFTAIHKHY SLDDWKLFAT NHPECLQNVA VSSGSGQNDL EKMTSILEAV PQVKFICLDV ANGYSEHFVE FVKLVRAKFP EHTIMAGNVV TGEMVEELIL SGADIIKVGV GPGSVCTTRT KTGVGYPQLS AVIECADSAH GLKGHIISDG GCTCPGDVAK AFGAGADFVM LGGMFSGHTE CAGEVIERNG RKLKLFYGMS SDTAMNKHAG GVAEYRASEG KTVEVPYKGD VENTILDILG GLRSTCTYVG AAKLKELSRR ATFIRVTQQH NTVFS.
Sequence Length
345
Related Product Information for GMPR recombinant protein
Description: GMPR Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 365 amino acids (1-345) and having a molecular mass of 39.5kDa.GMPR is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Guanosine monophosphate reductase (GMPR) catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. GMPR acts in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in upholding the intracellular balance of A and G nucleotides. In addition, the GMPR protein functions in the re-utilization of free intracellular bases and purine nucleosides.
Introduction: Guanosine monophosphate reductase (GMPR) catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. GMPR acts in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in upholding the intracellular balance of A and G nucleotides. In addition, the GMPR protein functions in the re-utilization of free intracellular bases and purine nucleosides.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
37,419 Da
NCBI Official Full Name
GMP reductase 1
NCBI Official Synonym Full Names
guanosine monophosphate reductase
NCBI Official Symbol
GMPR
NCBI Official Synonym Symbols
GMPR1
NCBI Protein Information
GMP reductase 1; guanine monophosphate reductase; guanosine 5'-monophosphate oxidoreductase 1; guanosine monophosphate reductase 1
UniProt Protein Name
GMP reductase 1
Protein Family
UniProt Gene Name
GMPR
UniProt Synonym Gene Names
GMPR1; Guanosine monophosphate reductase 1
UniProt Entry Name
GMPR1_HUMAN
NCBI Description
This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.[provided by RefSeq, Oct 2009]
Uniprot Description
GMPR: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Belongs to the IMPDH/GMPR family.
Protein type: Nucleotide Metabolism - purine; Oxidoreductase; EC 1.7.1.7
Chromosomal Location of Human Ortholog: 6p23
Cellular Component: cytosol
Molecular Function: GMP reductase activity; metal ion binding
Biological Process: nucleobase, nucleoside and nucleotide metabolic process; nucleotide metabolic process; response to cold; purine base metabolic process; purine salvage
Research Articles on GMPR
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Product Notes
The GMPR gmpr (Catalog #AAA145233) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MPRIDADLKL DFKDVLLRPK RSSLKSRAEV DLERTFTFRN SKQTYSGIPI IVANMDTVGT FEMAAVMSQH SMFTAIHKHY SLDDWKLFAT NHPECLQNVA VSSGSGQNDL EKMTSILEAV PQVKFICLDV ANGYSEHFVE FVKLVRAKFP EHTIMAGNVV TGEMVEELIL SGADIIKVGV GPGSVCTTRT KTGVGYPQLS AVIECADSAH GLKGHIISDG GCTCPGDVAK AFGAGADFVM LGGMFSGHTE CAGEVIERNG RKLKLFYGMS SDTAMNKHAG GVAEYRASEG KTVEVPYKGD VENTILDILG GLRSTCTYVG AAKLKELSRR ATFIRVTQQH NTVFS.. It is sometimes possible for the material contained within the vial of "Guanosine Monophosphate Reductase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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