Glucocorticoid modulatory element-binding protein 1 (GMEB1) Recombinant Protein | GMEB1 recombinant protein
Recombinant Human Glucocorticoid modulatory element-binding protein 1 (GMEB1)
Gene Names
GMEB1; PIF96; P96PIF
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Glucocorticoid modulatory element-binding protein 1 (GMEB1); Recombinant Human Glucocorticoid modulatory element-binding protein 1 (GMEB1); GMEB1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-573, Full length protein
Sequence
ANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGLFIDGHFYNRIYEAGSENNTAVVAVETHTIHKIEEGIDTGTIEANEDMEIAYPITCGESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGSITQIAISEESMEEAGLEWNSALTAAVTMATEEGVKKDSEEISEDTLMFWKGIADVGLMEEVVCNIQKEIEELLRGVQQRLIQAPFQVTDAAVLNNVAHTFGLMDTVKKVLDNRRNQVEQGEEQFLYTLTDLERQLEEQKKQGQDHRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPPVQQPQFTVISPITITPVGQSFSMGNIPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSSSPDTVTIHPSSSLALLSSTAMQDGSTLGNMTTMVSPVELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDPEAEDTEGKAVILETELRTEEKVVAEMEEHQHQVHNVEIVVLED
Sequence Length
572
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for GMEB1 recombinant protein
This gene is a member of KDWK gene family. The product of this gene associates with GMEB2 protein, and the complex is essential for parvovirus DNA replication. Study of rat homolog implicates the role of this gene in modulation of transactivation by the glucocorticoid receptor bound to glucocorticoid response elements. Two alternative spliced transcript variants encoding different isoforms exist.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
61,327 Da
NCBI Official Full Name
glucocorticoid modulatory element-binding protein 1 isoform 3
NCBI Official Synonym Full Names
glucocorticoid modulatory element binding protein 1
NCBI Official Symbol
GMEB1
NCBI Official Synonym Symbols
PIF96; P96PIF
NCBI Protein Information
glucocorticoid modulatory element-binding protein 1
UniProt Protein Name
Glucocorticoid modulatory element-binding protein 1
Protein Family
UniProt Gene Name
GMEB1
UniProt Synonym Gene Names
GMEB-1; PIF p96
NCBI Description
This gene encodes a member of KDWK gene family which associates with GMEB2 protein. The GMEB1-GMEB2 complex is essential for parvovirus DNA replication. Studies in rat for a similar gene suggest that this gene's role is to modulate the transactivation of the glucocorticoid receptor when it is bound to glucocorticoid response elements. Three alternative spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Feb 2016]
Uniprot Description
Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.
Research Articles on GMEB1
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Product Notes
The GMEB1 gmeb1 (Catalog #AAA1399315) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-573, Full length protein. The amino acid sequence is listed below: ANAEVSVPVG DVVVVPTEGN EGENPEDTKT QVILQLQPVQ QGLFIDGHFY NRIYEAGSEN NTAVVAVETH TIHKIEEGID TGTIEANEDM EIAYPITCGE SKAILLWKKF VCPGINVKCV KFNDQLISPK HFVHLAGKST LKDWKRAIRL GGIMLRKMMD SGQIDFYQHD KVCSNTCRST KFDLLISSAR APVPGQQTSV VQTPTSADGS ITQIAISEES MEEAGLEWNS ALTAAVTMAT EEGVKKDSEE ISEDTLMFWK GIADVGLMEE VVCNIQKEIE ELLRGVQQRL IQAPFQVTDA AVLNNVAHTF GLMDTVKKVL DNRRNQVEQG EEQFLYTLTD LERQLEEQKK QGQDHRLKSQ TVQNVVLMPV STPKPPKRPR LQRPASTTVL SPSPPVQQPQ FTVISPITIT PVGQSFSMGN IPVATLSQGS SPVTVHTLPS GPQLFRYATV VSSAKSSSPD TVTIHPSSSL ALLSSTAMQD GSTLGNMTTM VSPVELVAME SGLTSAIQAV ESTSEDGQTI IEIDPAPDPE AEDTEGKAVI LETELRTEEK VVAEMEEHQH QVHNVEIVVL ED. It is sometimes possible for the material contained within the vial of "Glucocorticoid modulatory element-binding protein 1 (GMEB1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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