Glutaminase liver isoform, mitochondrial (Gls2) Recombinant Protein | Gls2 recombinant protein
Recombinant Rat Glutaminase liver isoform, mitochondrial (Gls2)
Gene Names
Gls2; Ga
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Glutaminase liver isoform; mitochondrial (Gls2); Recombinant Rat Glutaminase liver isoform; Gls2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
15-602, Full length protein
Sequence
GSHGQRGGWGHPSRGPLLGGGVRYYFGEAAAQGRGTPHSHQPQHSDHDASNSGMLPRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLQDCMSKMQRMVQESSSGGLLDRELFQKCVSSNIVLLTQAFRKKFVIPDFEEFTGHVDRIFEDAKELTGGKVAAYIPHLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISVSTLGTDYVHKFVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAGNEFMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGAILLVVPNVMGMMCLSPPLDKLGNSHRGISFCQKLVSLFNFHNYDNLRHCARKLDPRREGGEVRNKTVVNLLFAAYSGDVSALRRFALSAVDMEQKDYDSRTALHVAAAEGHIDVVKFLIEACKVNPFVKDRWGNIPLDDAVQFNHLEVVKLLQDYHDSYMLSETQAEVAAETLSKENLESMV
Sequence Length
588
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Gls2 recombinant protein
This protein is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well. At least one transcribed pseudogene has been found for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
59,204 Da
NCBI Official Full Name
glutaminase liver isoform, mitochondrial isoform 1
NCBI Official Synonym Full Names
glutaminase 2
NCBI Official Symbol
Gls2
NCBI Official Synonym Symbols
Ga
NCBI Protein Information
glutaminase liver isoform, mitochondrial
UniProt Protein Name
Glutaminase liver isoform, mitochondrial
Protein Family
UniProt Gene Name
Gls2
UniProt Synonym Gene Names
Ga; GLS
NCBI Description
first enzyme of glutamine catabolism in liver [RGD, Feb 2006]
Uniprot Description
Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production ().
Research Articles on Gls2
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Product Notes
The Gls2 gls2 (Catalog #AAA967227) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 15-602, Full length protein. The amino acid sequence is listed below: GSHGQRGGWG HPSRGPLLGG GVRYYFGEAA AQGRGTPHSH QPQHSDHDAS NSGMLPRLGD LLFYTIAEGQ ERIPIHKFTT ALKATGLQTS DPRLQDCMSK MQRMVQESSS GGLLDRELFQ KCVSSNIVLL TQAFRKKFVI PDFEEFTGHV DRIFEDAKEL TGGKVAAYIP HLAKSNPDLW GVSLCTVDGQ RHSVGHTKIP FCLQSCVKPL TYAISVSTLG TDYVHKFVGK EPSGLRYNKL SLNEEGIPHN PMVNAGAIVV SSLIKMDCNK AEKFDFVLQY LNKMAGNEFM GFSNATFQSE KETGDRNYAI GYYLKEKKCF PKGVDMMAAL DLYFQLCSVE VTCESGSVMA ATLANGGICP ITGESVLSAE AVRNTLSLMH SCGMYDFSGQ FAFHVGLPAK SAVSGAILLV VPNVMGMMCL SPPLDKLGNS HRGISFCQKL VSLFNFHNYD NLRHCARKLD PRREGGEVRN KTVVNLLFAA YSGDVSALRR FALSAVDMEQ KDYDSRTALH VAAAEGHIDV VKFLIEACKV NPFVKDRWGN IPLDDAVQFN HLEVVKLLQD YHDSYMLSET QAEVAAETLS KENLESMV. It is sometimes possible for the material contained within the vial of "Glutaminase liver isoform, mitochondrial (Gls2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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