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Gamma-glutamyl hydrolase (GGH) Recombinant Protein | GGH recombinant protein

Recombinant Bovine Gamma-glutamyl hydrolase (GGH)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Gamma-glutamyl hydrolase (GGH); Recombinant Bovine Gamma-glutamyl hydrolase (GGH); GGH recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
25-318, Full length protein
Sequence
APPAPTPKKPIIGILMQKCHNKNMRALGKYYIAASYVKFLESAGARVVPVRLDLKNEEYEKLFKSINGVLFPGGSVNLMRSGYARVAKMFYNLSIKSFGEGDYFPVWGTCLGFEELIYLVSGESLLTLTDTVGIKLPLNFSRGTLQSRMFQNFPADLLLSLAVEPLTAHFHKWSLSVMNFTKNEKLKAFFSILTTNTDGNIDFISTMEGYRYPIYGVQWHPEKAPYEWGQLRGISHAPNAVKAAFYLAEFFVAEARKSNHHFESDVEETKALIYQYRPTYTGNVSSFQQSYIFD
Sequence Length
294
Species
Bovine
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for GGH recombinant protein
This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,683 Da
NCBI Official Full Name
gamma-glutamyl hydrolase
NCBI Official Synonym Full Names
gamma-glutamyl hydrolase
NCBI Official Symbol
GGH
NCBI Protein Information
gamma-glutamyl hydrolase
UniProt Protein Name
Gamma-glutamyl hydrolase
Protein Family
UniProt Gene Name
GGH

Uniprot Description

Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates. Exhibits either endo- or exopeptidase activity depending upon the tissue of origin. When secreted, it acts primarily as an endopeptidase ().

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Product Notes

The GGH ggh (Catalog #AAA1002569) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 25-318, Full length protein. The amino acid sequence is listed below: APPAPTPKKP IIGILMQKCH NKNMRALGKY YIAASYVKFL ESAGARVVPV RLDLKNEEYE KLFKSINGVL FPGGSVNLMR SGYARVAKMF YNLSIKSFGE GDYFPVWGTC LGFEELIYLV SGESLLTLTD TVGIKLPLNF SRGTLQSRMF QNFPADLLLS LAVEPLTAHF HKWSLSVMNF TKNEKLKAFF SILTTNTDGN IDFISTMEGY RYPIYGVQWH PEKAPYEWGQ LRGISHAPNA VKAAFYLAEF FVAEARKSNH HFESDVEETK ALIYQYRPTY TGNVSSFQQS YIFD. It is sometimes possible for the material contained within the vial of "Gamma-glutamyl hydrolase (GGH), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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