GDNF family receptor alpha-3 (Gfra3) Recombinant Protein | Gfra3 recombinant protein
Recombinant Mouse GDNF family receptor alpha-3 (Gfra3)
Gene Names
Gfra3; Y15110; GFRalpha3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
GDNF family receptor alpha-3 (Gfra3); Recombinant Mouse GDNF family receptor alpha-3 (Gfra3); Gfra3 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
29-371, Full length protein
Sequence
NSLATENRFVNSCTQARKKCEANPACKAAYQHLGSCTSSLSRPLPLEESAMSADCLEAAEQLRNSSLIDCRCHRRMKHQATCLDIYWTVHPARSLGDYELDVSPYEDTVTSKPWKMNLSKLNMLKPDSDLCLKFAMLCTLHDKCDRLRKAYGEACSGIRCQRHLCLAQLRSFFEKAAESHAQGLLLCPCAPEDAGCGERRRNTIAPSCALPSVTPNCLDLRSFCRADPLCRSRLMDFQTHCHPMDILGTCATEQSRCLRAYLGLIGTAMTPNFISKVNTTVALSCTCRGSGNLQDECEQLERSFSQNPCLVEAIAAKMRFHRQLFSQDWADSTFSVVQQQNSN
Sequence Length
343
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Gfra3 recombinant protein
This protein is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44,307 Da
NCBI Official Full Name
GDNF family receptor alpha-3 preproprotein
NCBI Official Synonym Full Names
glial cell line derived neurotrophic factor family receptor alpha 3
NCBI Official Symbol
Gfra3
NCBI Official Synonym Symbols
Y15110; GFRalpha3
NCBI Protein Information
GDNF family receptor alpha-3
UniProt Protein Name
GDNF family receptor alpha-3
Protein Family
UniProt Gene Name
Gfra3
UniProt Synonym Gene Names
GDNF receptor alpha-3; GDNFR-alpha-3; GFR-alpha-3
NCBI Description
This gene encodes a cell surface glycoprotein and member of the glial cell line-derived neurotrophic receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein mediates binding of the ligand artemin to the ret receptor tyrosine kinase, and this interaction may regulate thermal pain and axon regeneration. Homozygous knockout mice for this gene exhibit impaired proliferation of cultured neuroblasts and impaired development of the superior cervical ganglion. [provided by RefSeq, Aug 2015]
Uniprot Description
Receptor for the glial cell line-derived neurotrophic factor, artemin. Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase ().
Research Articles on Gfra3
Similar Products
Product Notes
The Gfra3 gfra3 (Catalog #AAA1087005) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 29-371, Full length protein. The amino acid sequence is listed below: NSLATENRFV NSCTQARKKC EANPACKAAY QHLGSCTSSL SRPLPLEESA MSADCLEAAE QLRNSSLIDC RCHRRMKHQA TCLDIYWTVH PARSLGDYEL DVSPYEDTVT SKPWKMNLSK LNMLKPDSDL CLKFAMLCTL HDKCDRLRKA YGEACSGIRC QRHLCLAQLR SFFEKAAESH AQGLLLCPCA PEDAGCGERR RNTIAPSCAL PSVTPNCLDL RSFCRADPLC RSRLMDFQTH CHPMDILGTC ATEQSRCLRA YLGLIGTAMT PNFISKVNTT VALSCTCRGS GNLQDECEQL ERSFSQNPCL VEAIAAKMRF HRQLFSQDWA DSTFSVVQQQ NSN. It is sometimes possible for the material contained within the vial of "GDNF family receptor alpha-3 (Gfra3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
