Related Product Information for SCO6604 assay kit
Background/Introduction: beta-catenin is a 781 amino acid adherens junction protein that plays an important role in two unrelated cellular functions. Adherens junctions are critical for establishment and maintenance of epithelial layers, such as those found lining the surface of organs. Involved in both cell-cell adhesion and in the wnt/wg signaling pathway, beta-catenin can be found in the cytoplasm or the nucleus3. In the cytoplasm, beta-catenin is unstabilized by phosphorylation and association with E-cadherin. When beta-catenin translocates to the nucleus, it has comparatively low levels of phosphorylation. Wnt/wg signaling results in beta-catenin accumulation and transcriptional activation of specific target genes during development. Deregulation of beta-catenin signaling is an important event in the evolution a number of malignancies, including colon cancer4, melanoma, ovarian cancer5, and prostate cancer6. The homology between human, mouse and rat beta-catenin is 99.9%.
Product Notes
The General SCO6604 (Catalog #
AAA8243231) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA8243231 Assay Kit recognizes General SCO6604. AAA Biotech's Beta-Glucosidase can be used in a range of immunoassay formats including, but not limited to, Functional Assay. Researchers should empirically determine the suitability of the SCO6604 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
It is sometimes possible for the material contained within the vial of
"Beta-Glucosidase, Assay Kit" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech
cannot be held
responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any
aspect of this datasheet at
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