Canine GDP Dissociation Inhibitor 1 ELISA Kit | GDI1 elisa kit
Canine GDP Dissociation Inhibitor 1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. [provided by RefSeq, Jul 2008]
Uniprot Description
GDI1: a GDP dissociation inhibitor protein expressed primarily in neural and sensory tissues. GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the Rab family, small GTP-binding proteins of the Ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from Rab proteins and release GDP from membrane-bound Rabs. Mutations have been linked to X-linked nonspecific mental retardation.
Protein type: Motility/polarity/chemotaxis; G protein regulator, misc.
Chromosomal Location of Human Ortholog: Xq28
Cellular Component: Golgi apparatus; neuron projection; protein complex; cytoplasm; midbody; cytosol
Molecular Function: protein binding; GDP-dissociation inhibitor activity; Rab GDP-dissociation inhibitor activity; GTPase activator activity; Rab GTPase binding
Biological Process: regulation of small GTPase mediated signal transduction; protein transport; small GTPase mediated signal transduction; negative regulation of axonogenesis; Rab protein signal transduction; signal transduction; response to calcium ion; positive regulation of GTPase activity
Disease: Mental Retardation, X-linked 41
Research Articles on GDI1
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Product Notes
The Canine GDI1 gdi1 (Catalog #AAA734759) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA734759 ELISA Kit recognizes Canine GDI1. It is sometimes possible for the material contained within the vial of "GDP Dissociation Inhibitor 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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