Human grancalcin, EF-hand calcium binding protein ELISA Kit | GCA elisa kit

Human Grancalcin, GCA ELISA Kit

Cat. Num. AAA9337037

• Gene Names: GCA; GCL
• Reactivity: Human
• Synonyms: grancalcin; EF-hand calcium binding protein; Human Grancalcin; GCA ELISA Kit; Human Grancalcin (GCA) ELISA kit; GCL; EF-hand calcium-binding protein; penta-EF-hand protein; GCA elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Monkey Body Fluids And Tissue Homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 25pg/ml-800pg/ml
• Sensitivity: 2.0pg/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for GCA elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of GC (hereafter termed "analyte") in undiluted original Monkey body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 6912388
• NCBI GeneID: 25801
• NCBI Accession #: NP_036330.1
• NCBI GenBank Nucleotide #: NM_012198.3
• UniProt Accession #: P28676; Q53TB5; Q59EP3; B2R5X3
• Molecular Weight: 24,010 Da
• NCBI Official Full Name: grancalcin
• NCBI Official Synonym Full Names: grancalcin, EF-hand calcium binding protein
• NCBI Official Symbol: GCA
• NCBI Official Synonym Symbols: GCL
• NCBI Protein Information: grancalcin; grancalcin, penta-EF-hand protein; grancalcin, EF-hand calcium-binding protein
• UniProt Protein Name: Grancalcin
• Protein Family: Grancalcin
• UniProt Gene Name: GCA
• UniProt Synonym Gene Names: GCL
• UniProt Entry Name: GRAN_HUMAN

NCBI Description

This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation. [provided by RefSeq, Jul 2008]

Uniprot Description

GCA: Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 2q24.2

Cellular Component: cytoplasm; plasma membrane

Molecular Function: protein homodimerization activity; protein heterodimerization activity; calcium-dependent cysteine-type endopeptidase activity; calcium ion binding

Biological Process: proteolysis