Rat Transcription factor GATA-4 ELISA Kit | Gata4 elisa kit

Rat Transcription factor GATA-4 ELISA Kit

Cat. Num. AAA2880650

• Reactivity: Rat
• Synonyms: Transcription factor GATA-4; Rat Transcription factor GATA-4 ELISA Kit; DNA-binding protein GATA-GT2; GATA-binding factor 4; Gata4; Gata4 elisa kit

• Reactivity: Rat
• Sequence Length: 440

• Assay Type: Sandwich
• Detection Range: 0.156-10 ng/mL
• Sensitivity: 0.091 ng/mL
• Intra-Assay CV: <=4.6%
• Inter-Assay CV: <=8.4%
• Recovery: 90%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 25282465
• NCBI GeneID: 54254
• NCBI Accession #: NP_653331.1
• NCBI GenBank Nucleotide #: NM_144730.1
• UniProt Accession #: P46152
• Molecular Weight: 44,597 Da
• NCBI Official Full Name: transcription factor GATA-4
• NCBI Official Synonym Full Names: GATA binding protein 4
• NCBI Official Symbol: Gata4
• NCBI Protein Information: transcription factor GATA-4
• UniProt Protein Name: Transcription factor GATA-4
• Protein Family: Transcription factor
• UniProt Gene Name: Gata4
• UniProt Entry Name: GATA4_RAT

NCBI Description

plays a role in regulation of cardiac-myocyte specific gene expression; interacts with dHAND (HAND2) to activate transcription of several cardiac-specific genes [RGD, Feb 2006]

Uniprot Description

GATA4: a conserved and ubiquitous member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. May regulate a set of cardiac-specific genes and play a crucial role in cardiogenesis. Defects are a cause of atrial septal defect 2 (ASD2). ASD2 is an autosomal dominant condition with atrial septal defect and other congenital heart disease but no conduction defects or noncardiac abnormalities.

Protein type: Motility/polarity/chemotaxis; Transcription factor

Cellular Component: nuclear chromatin; nucleus; transcription factor complex

Molecular Function: chromatin binding; DNA binding; NFAT protein binding; protein kinase binding; RNA polymerase II transcription factor activity, enhancer binding; sequence-specific DNA binding; transcription activator binding; transcription coactivator activity; transcription factor activity; transcription factor binding; zinc ion binding

Biological Process: anatomical structure formation; BMP signaling pathway; cardiac muscle cell differentiation; cardiac muscle development; cardiac muscle hypertrophy; cell fate commitment; cell-cell signaling; embryonic digestive tract morphogenesis; embryonic foregut morphogenesis; embryonic heart tube anterior/posterior pattern formation; embryonic heart tube development; embryonic morphogenesis; endoderm formation; gastrulation with mouth forming second; gut development; heart development; heart looping; heart morphogenesis; in utero embryonic development; male gonad development; negative regulation of autophagy; organ morphogenesis; positive regulation of angiogenesis; positive regulation of BMP signaling pathway; positive regulation of cardiac muscle cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of cardiac muscle cell proliferation; regulation of gene expression; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; response to drug; response to estrogen stimulus; response to mechanical stimulus; response to retinoic acid; response to vitamin A; Sertoli cell differentiation; spermatogenesis; transcription from RNA polymerase II promoter; tube morphogenesis; Wnt receptor signaling pathway through beta-catenin