Mouse Transcription factor AP-1 ELISA Kit | Jun elisa kit

Mouse Transcription factor AP-1 ELISA Kit

Cat. Num. AAA2881728

• Gene Names: Jun; AP-1; Junc; c-jun
• Reactivity: Mouse
• Synonyms: Transcription factor AP-1; Mouse Transcription factor AP-1 ELISA Kit; AH119; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; Jun A; Jun; Jun elisa kit

• Reactivity: Mouse
• Sequence Length: 334

• Assay Type: Sandwich
• Detection Range: 7.8-500 ng/mL
• Sensitivity: 4.04 ng/mL
• Intra-Assay CV: <=8.3%
• Inter-Assay CV: <=10.3%
• Recovery: 90%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 6754402
• NCBI GeneID: 16476
• NCBI Accession #: NP_034721.1
• NCBI GenBank Nucleotide #: NM_010591.2
• UniProt Accession #: P05627
• Molecular Weight: 35,944 Da
• NCBI Official Full Name: transcription factor AP-1
• NCBI Official Synonym Full Names: jun proto-oncogene
• NCBI Official Symbol: Jun
• NCBI Official Synonym Symbols: AP-1; Junc; c-jun
• NCBI Protein Information: transcription factor AP-1
• UniProt Protein Name: Transcription factor AP-1
• Protein Family: Transcription factor
• UniProt Gene Name: Jun
• UniProt Synonym Gene Names: AP1; Jun A
• UniProt Entry Name: JUN_MOUSE

Uniprot Description

Jun: the protooncogene c-Jun is a component of the transcription factor AP-1, which binds and activates transcription at TRE/AP-1 elements. The Jun Kinases (JNKs) binds to the N-terminal region of c-Jun and phosphorylate it in response to extracellular signals including growth factors, cytokines and stress, regulating its transcriptional activity.

Protein type: Transcription factor; Oncoprotein

Cellular Component: cytosol; nuclear chromatin; nucleoplasm; nucleus; transcription factor complex; transcriptional repressor complex

Molecular Function: chromatin binding; DNA binding; double-stranded DNA binding; enzyme binding; GTPase activator activity; identical protein binding; protein binding; protein heterodimerization activity; protein homodimerization activity; RNA polymerase II transcription factor activity, enhancer binding; sequence-specific DNA binding; transcription activator binding; transcription coactivator activity; transcription factor activity; transcription factor binding

Biological Process: angiogenesis; axon regeneration; cellular process; cellular response to hormone stimulus; cellular response to potassium ion starvation; leading edge cell differentiation; learning; liver development; membrane depolarization; microglial cell activation; monocyte differentiation; negative regulation of apoptosis; negative regulation of cell proliferation; negative regulation of DNA binding; negative regulation of neuron apoptosis; negative regulation of protein amino acid autophosphorylation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of apoptosis; positive regulation of cell differentiation; positive regulation of cell proliferation; positive regulation of DNA replication; positive regulation of endothelial cell proliferation; positive regulation of fibroblast proliferation; positive regulation of GTPase activity; positive regulation of monocyte differentiation; positive regulation of neuron apoptosis; positive regulation of smooth muscle cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of cell cycle; regulation of transcription, DNA-dependent; release of cytochrome c from mitochondria; response to cAMP; response to cytokine stimulus; response to drug; response to lipopolysaccharide; response to radiation; SMAD protein nuclear translocation; transcription from RNA polymerase II promoter; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway