FRAS1-related extracellular matrix protein 1 (FREM1) Recombinant Protein | FREM1 recombinant protein

Recombinant Human FRAS1-related extracellular matrix protein 1 (FREM1) , partial

• Gene Names: FREM1; BNAR; MOTA; TILRR; TRIGNO2; C9orf143; C9orf145; C9orf154
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: FRAS1-related extracellular matrix protein 1 (FREM1); Recombinant Human FRAS1-related extracellular matrix protein 1 (FREM1); partial; FREM1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 222

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 295293182
• NCBI GeneID: 158326
• NCBI Accession #: NP_001171175.1
• NCBI GenBank Nucleotide #: NM_001177704.1
• UniProt Accession #: Q5H8C1; Q5VV00; Q5VV01; Q6MZI4; Q8NEG9; Q96LI3; B7ZBX4
• Molecular Weight: 25,008 Da
• NCBI Official Full Name: FRAS1-related extracellular matrix protein 1 isoform 2
• NCBI Official Synonym Full Names: FRAS1 related extracellular matrix 1
• NCBI Official Symbol: FREM1
• NCBI Official Synonym Symbols: BNAR; MOTA; TILRR; TRIGNO2; C9orf143; C9orf145; C9orf154
• NCBI Protein Information: FRAS1-related extracellular matrix protein 1
• UniProt Protein Name: FRAS1-related extracellular matrix protein 1
• Protein Family: FRAS1-related extracellular matrix protein
• UniProt Gene Name: FREM1

NCBI Description

This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation. [provided by RefSeq, Apr 2011]

Uniprot Description

Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development.