Fibronectin Leucine Rich Transmembrane Protein 1 (FLRT1) Recombinant Protein | FLRT1 recombinant protein

Recombinant Fibronectin Leucine Rich Transmembrane Protein 1 (FLRT1)

Cat. Num. AAA2086912

• Gene Names: FLRT1; SPG68
• Applications: SDS-Page, Western Blot
• Purity: > 95%
• Synonyms: Fibronectin Leucine Rich Transmembrane Protein 1 (FLRT1); Recombinant Fibronectin Leucine Rich Transmembrane Protein 1 (FLRT1); Fibronectin-like domain-containing leucine-rich transmembrane protein 1; Leucine-rich repeat transmembrane protein FLRT1; FLRT1 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Freeze-dried powder
• Sequence Length: 674

• Applicable Applications for FLRT1 recombinant protein: Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
• Fragment: Ser345~Asn516
• Tag: N-terminal His-tag
• Buffer Formulation: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Source Note: Prokaryotic expression
• Organism Species: Human
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Isoelectric Point: 5.3
• Subcellular Location: Membrane. Single-pass Type I Membrane Protein.
• Usage: Reconstitute in sterile ddH2O.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

Product Categories/Family for FLRT1 recombinant protein

Recombinant Protein

NCBI and Uniprot Product Information

• NCBI GI #: 34577057
• NCBI GeneID: 23769
• NCBI Accession #: NP_037412.2
• NCBI GenBank Nucleotide #: NM_013280.4
• UniProt Accession #: Q9NZU1; Q8WVA2
• Molecular Weight: 22.0kDa
• NCBI Official Full Name: leucine-rich repeat transmembrane protein FLRT1
• NCBI Official Synonym Full Names: fibronectin leucine rich transmembrane protein 1
• NCBI Official Symbol: FLRT1
• NCBI Official Synonym Symbols: SPG68
• NCBI Protein Information: leucine-rich repeat transmembrane protein FLRT1
• UniProt Protein Name: Leucine-rich repeat transmembrane protein FLRT1
• Protein Family: Leucine-rich repeat transmembrane protein
• UniProt Gene Name: FLRT1

NCBI Description

This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain. [provided by RefSeq, Jul 2008]

Uniprot Description

FLRT1: May have a function in cell adhesion and/or receptor signaling.

Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: cytoplasm; cytoplasmic vesicle; focal adhesion; integral to plasma membrane; intercellular junction; perinuclear region of cytoplasm; plasma membrane

Molecular Function: protein kinase inhibitor activity

Biological Process: cytokine and chemokine mediated signaling pathway; dendrite development; fibroblast growth factor receptor signaling pathway; negative regulation of JAK-STAT cascade; negative regulation of protein kinase activity