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SDS-PAGE

Fetuin-B / FETUB Recombinant Protein | FETUB recombinant protein

Recombinant Mouse Fetuin-B / FETUB Protein (His tag)

Gene Names
Fetub; Gugu; D17980; AI255764; 2310011O17Rik
Purity
> 97 % as determined by SDS-PAGE
Synonyms
Fetuin-B / FETUB; Recombinant Mouse Fetuin-B / FETUB Protein (His tag); 2310011O17Rik; AI255764; D17980; Gugu; FETUB recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
> 97 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile 20mM Tris, 150mM NaCl, pH 7.5
Sequence Length
308
Application Notes
The recombinant mouse FETUB consists of 381 amino acids and has a predicted molecular mass of 42.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmFETUB is approximately 55-60 kDa due to high glycosylation.
Predicted N Terminal
Arg 19
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C

SDS-PAGE

SDS-PAGE
Related Product Information for FETUB recombinant protein
Background: Fetuin-B, also known as Fetuin-like protein IRL685 and FETUB, is a secreted protein which belongs to the fetuin family. Fetuin-B / FETUB contains two cystatin domains. Fetuin-B is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption. Fetuin-A has been identified as a major protein during fetal life and is also involved in important functions such as protease inhibitory activities and development-associated regulation of calcium metabolism and osteogenesis. Fetuin-A is a key partner in the recovery phase of an acute inflammatory response. Fetuin-B / FETUB is found at least in human and rodents. It is unambiguously a paralogue of Fetuin-A. Fetuin-A and Fetuin-B exhibit significant differences at the amino acid sequence level, notably including variations with respect to the archetypal fetuin-specific signature.

Description: A DNA sequence encoding the extracellular domain of mouse FETUB (Q9QXC1-1) (Met 1-Pro 388) was expressed, with a polyhistidine tag at the C-terminus.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,713 Da
NCBI Official Full Name
fetuin-B isoform 2
NCBI Official Synonym Full Names
fetuin beta
NCBI Official Symbol
Fetub
NCBI Official Synonym Symbols
Gugu; D17980; AI255764; 2310011O17Rik
NCBI Protein Information
fetuin-B
UniProt Protein Name
Fetuin-B
Protein Family
UniProt Gene Name
Fetub

Uniprot Description

FETUB: is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and response to systemic inflammation. This protein may be secreted by cells. [provided by RefSeq, Jul 2008]

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16 B1|16 13.76 cM

Cellular Component: extracellular region

Molecular Function: metalloendopeptidase inhibitor activity

Biological Process: binding of sperm to zona pellucida; single fertilization

Research Articles on FETUB

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Product Notes

The FETUB fetub (Catalog #AAA2546908) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse FETUB consists of 381 amino acids and has a predicted molecular mass of 42.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmFETUB is approximately 55-60 kDa due to high glycosylation. Researchers should empirically determine the suitability of the FETUB fetub for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Fetuin-B / FETUB, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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