Western Blot (WB)
(Anti- SOX1 Picoband antibody, MBS178398, Western blottingAll lanes: Anti SOX1 (MBS178398) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: NIH3T3 Whole Cell Lysate at 40ugPredicted bind size: 39KDObserved bind size: 39KD)
SOX1 Polyclonal Antibody | anti-SOX1 antibody
Anti-SOX1 Antibody
Predicted to work with: Human
Predicted to work with: Human
Western Blot (WB)
(Anti- SOX1 Picoband antibody, MBS178398, Western blottingAll lanes: Anti SOX1 (MBS178398) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: NIH3T3 Whole Cell Lysate at 40ugPredicted bind size: 39KDObserved bind size: 39KD)
Western Blot (WB)
(Anti- SOX1 Picoband antibody, MBS178398, Western blottingAll lanes: Anti SOX1 (MBS178398) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: NIH3T3 Whole Cell Lysate at 40ugPredicted bind size: 39KDObserved bind size: 39KD)
Background: SOX1 (for Sex determining region Y-box 1), located in 13q34, is a transcription factor in the Sox protein family. It means that this intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. SOX1 expression is restricted to neuroectodermin the tetrapod embryo. It is expressed particularly in the ventral striatum.
NCBI and Uniprot Product Information
NCBI Description
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. [provided by RefSeq, Jul 2008]
Uniprot Description
SOX1: Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Mainly expressed in the developing central nervous system.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 13q34
Cellular Component: nucleus
Molecular Function: DNA binding; protein binding; transcription factor activity
Biological Process: establishment and/or maintenance of chromatin architecture; forebrain neuron development; lens morphogenesis in camera-type eye; neuron migration; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; ventral spinal cord interneuron specification
Research Articles on SOX1
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Product Notes
The SOX1 sox1 (Catalog #AAA178398) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-SOX1 Antibody reacts with Mouse, Rat Predicted to work with: Human and may cross-react with other species as described in the data sheet. AAA Biotech's SOX1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot Concentration: 0.1-0.5ug/ml. Researchers should empirically determine the suitability of the SOX1 sox1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SOX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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