High affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) Recombinant Protein | FCER1G recombinant protein

Recombinant Human High affinity immunoglobulin epsilon receptor subunit gamma (FCER1G), partial

Cat. Num. AAA9423258

• Gene Names: FCER1G; FCRG
• Reactivity: Human
• Purity: Greater than 90% as determined by SDS-PAGE.
• Synonyms: High affinity immunoglobulin epsilon receptor subunit gamma (FCER1G); Recombinant Human High affinity immunoglobulin epsilon receptor subunit gamma (FCER1G); partial; Fc receptor gamma-chain; FcRgamma; Fc-epsilon RI-gamma; IgE Fc receptor subunit gamma; FceRI gamma; FCER1G recombinant protein

• Host: E Coli
• Reactivity: Human
• Purity/Purification: Greater than 90% as determined by SDS-PAGE.
• Form/Format: Tris-based buffer, 50% glycerol
• Sequence Positions: Partial, 19-86aa

• Tag Info: N-terminal GST-tagged
• Preparation and Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.; Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.

Related Product Information for FCER1G recombinant protein

Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin.

NCBI and Uniprot Product Information

• NCBI GI #: 4758344
• NCBI GeneID: 2207
• NCBI Accession #: NP_004097.1
• NCBI GenBank Nucleotide #: NM_004106.1
• UniProt Accession #: P30273; Q5VTW4
• Molecular Weight: 31.27 kDa
• NCBI Official Full Name: high affinity immunoglobulin epsilon receptor subunit gamma
• NCBI Official Synonym Full Names: Fc fragment of IgE receptor Ig
• NCBI Official Symbol: FCER1G
• NCBI Official Synonym Symbols: FCRG
• NCBI Protein Information: high affinity immunoglobulin epsilon receptor subunit gamma
• UniProt Protein Name: High affinity immunoglobulin epsilon receptor subunit gamma
• Protein Family: High affinity immunoglobulin epsilon receptor
• UniProt Gene Name: FCER1G
• UniProt Synonym Gene Names: FcRgamma; FceRI gamma

NCBI Description

The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008]

Uniprot Description

FCER1G: Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin. Belongs to the CD3Z/FCER1G family.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: cell surface; external side of plasma membrane; Fc-epsilon receptor I complex; plasma membrane

Molecular Function: IgE binding; IgE receptor activity; IgG binding; protein binding; protein homodimerization activity

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; defense response to bacterium; Fc receptor mediated stimulatory signaling pathway; immunoglobulin mediated immune response; innate immune response; leukocyte migration; neutrophil activation during immune response; neutrophil chemotaxis; neutrophil degranulation; platelet activation; positive regulation of phagocytosis; protein homooligomerization; receptor internalization; stimulatory C-type lectin receptor signaling pathway; T cell differentiation during immune response