Family With Sequence Similarity 20 Recombinant Protein | FAM20A recombinant protein

Recombinant Family With Sequence Similarity 20, Member A (FAM20A)

Cat. Num. AAA2031685

• Gene Names: FAM20A; AI1G; AIGFS; FP2747
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: >95%
• Synonyms: Family With Sequence Similarity 20; Recombinant Family With Sequence Similarity 20; Member A (FAM20A); FAM20A recombinant protein

• Host: Host: E Coli; Source: Prokaryotic expression
• Purity/Purification: >95%
• Form/Format: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Sequence: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.; KEE WEVNPLYCDT VKQIYPYNNS QRLLNVIDMAIFDFLIGNMD RHHYEMFTKF GDDGFLIHLD NARGFGRHSH DEISILSPLSQCCMIKKKTL LHLQLLAQAD YRLSDVMRES LLEDQLSPVL TEPHLLALDRRLQTILRTVE GCIVAHGQQS VIVDGPVEQL APDSGQANLT S
• Sequence Length: 541

• Applicable Applications for FAM20A recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Predicted Molecular Mass: 23.5kDa
• Accurate Molecular Mass (KD): 24kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Expression System: Prokaryotic expression
• Tag: two N-terminal Tags, His-tag and S-tag
• Organism Species: Homo sapiens (Human)
• Fragment: Lys368~Ser541
• Usage: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 187951515
• NCBI GeneID: 54757
• Molecular Weight: 61,417 Da
• NCBI Official Full Name: Family with sequence similarity 20, member A
• NCBI Official Synonym Full Names: family with sequence similarity 20, member A
• NCBI Official Symbol: FAM20A
• NCBI Official Synonym Symbols: AI1G; AIGFS; FP2747
• NCBI Protein Information: pseudokinase FAM20A
• UniProt Protein Name: Pseudokinase FAM20A
• Protein Family: Pseudokinase
• UniProt Gene Name: FAM20A
• UniProt Entry Name: FA20A_HUMAN

NCBI Description

This locus encodes a protein that is likely secreted and may function in hematopoiesis. A mutation at this locus has been associated with amelogenesis imperfecta and gingival hyperplasia syndrome. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Aug 2011]

Uniprot Description

FAM20A: Defects in FAM20A are the cause of amelogenesis imperfecta and gingival fibromatosis syndrome (AIGFS). An autosomal recessive condition characterized by mild gingival fibromatosis and dental anomalies, including hypoplastic amelogenesis imperfecta, intrapulpal calcifications, delay of tooth eruption, hypodontia/oligodontia, pericoronal radiolucencies, and unerupted teeth. Belongs to the FAM20 family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17q24.2

Cellular Component: Golgi apparatus; cell

Biological Process: calcium ion homeostasis

Disease: Amelogenesis Imperfecta, Type Ig