Human family with sequence similarity 20, member A ELISA Kit | FAM20A elisa kit

Human Protein FAM20A, FAM20A ELISA Kit

Cat. Num. AAA924910

• Gene Names: FAM20A; AI1G; AIGFS; FP2747
• Reactivity: Human
• Synonyms: family with sequence similarity 20; member A; Human Protein FAM20A; FAM20A ELISA Kit; Human Protein FAM20A (FAM20A) ELISA kit; DKFZp434F2322; FP2747; ; FAM20A elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of human FAM20A. No significant cross-reactivity or interference between human FAM20A and analogues was observed.
• Sequence Length: 541

• Samples: Serum, plasma, tissue homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 0.156 ng/ml-10 ng/ml
• Sensitivity: <0.039 ng/ml
• Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
• Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
• Preparation and Storage: Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for FAM20A elisa kit

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for FAM20A has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any FAM20A present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for FAM20A is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of FAM20A bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

• NCBI GI #: 344198227
• NCBI GeneID: 54757
• NCBI Accession #: NP_001230675.1
• NCBI GenBank Nucleotide #: NM_001243746.1
• UniProt Accession #: Q96MK3; Q9UF95; B2RN47; B2RN49
• Molecular Weight: 61,417 Da
• NCBI Official Full Name: protein FAM20A isoform b
• NCBI Official Synonym Full Names: family with sequence similarity 20, member A
• NCBI Official Symbol: FAM20A
• NCBI Official Synonym Symbols: AI1G; AIGFS; FP2747
• NCBI Protein Information: protein FAM20A
• UniProt Protein Name: Protein FAM20A
• Protein Family: Pseudokinase
• UniProt Gene Name: FAM20A
• UniProt Synonym Gene Names: UNQ9388/PRO34279
• UniProt Entry Name: FA20A_HUMAN

NCBI Description

This locus encodes a protein that is likely secreted and may function in hematopoiesis. A mutation at this locus has been associated with amelogenesis imperfecta and gingival hyperplasia syndrome. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Aug 2011]

Uniprot Description

FAM20A: Defects in FAM20A are the cause of amelogenesis imperfecta and gingival fibromatosis syndrome (AIGFS). An autosomal recessive condition characterized by mild gingival fibromatosis and dental anomalies, including hypoplastic amelogenesis imperfecta, intrapulpal calcifications, delay of tooth eruption, hypodontia/oligodontia, pericoronal radiolucencies, and unerupted teeth. Belongs to the FAM20 family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17q24.2

Cellular Component: Golgi apparatus; cell

Biological Process: calcium ion homeostasis

Disease: Amelogenesis Imperfecta, Type Ig