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SDS-PAGE

BLBP / FABP7 recombinant protein

Recombinant Human BLBP / FABP7 Protein

Gene Names
FABP7; MRG; BLBP; FABPB; B-FABP
Purity
> 95 % as determined by SDS-PAGE
Synonyms
BLBP / FABP7; Recombinant Human BLBP / FABP7 Protein; FABP7; BLBP; FABPB; MRG; BLBP / FABP7 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
166
Application Notes
The recombinant human FABP7 consists of 132 amino acids and predicts a molecular mass of 14.9 KDa. It migrates as an approximately 16 KDa band in SDS-PAGE under reducing conditions.
Predicted N Terminal
Met
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C

SDS-PAGE

SDS-PAGE
Related Product Information for BLBP / FABP7 recombinant protein
Background: BLBP, also known as FABP7, is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP7 binds DHA with the highest affinity among all of the FABPs. FABPs may play roles in fatty acid uptake, transport, and metabolism. BLBP is expressed, during development, in radial glia by the activation of notch receptors. It was shown that reelin induces FABP7 expression in neural progenitor cells via notch-1 activation. BLBP variation is linked to weak prepulse inhibition (PPI) in mice and deficit in PPI is an endophenotypic trait observed in schizophrenia patients and their relatives.

Description: A DNA sequence encoding the mature form of human FABP7 (O15540) (Met1-Ala132) was expressed.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,829 Da
NCBI Official Full Name
fatty acid-binding protein, brain isoform 2
NCBI Official Synonym Full Names
fatty acid binding protein 7
NCBI Official Symbol
FABP7
NCBI Official Synonym Symbols
MRG; BLBP; FABPB; B-FABP
NCBI Protein Information
fatty acid-binding protein, brain
UniProt Protein Name
Fatty acid-binding protein, brain
UniProt Gene Name
FABP7
UniProt Synonym Gene Names
BLBP; FABPB; MRG; BLBP; B-FABP

NCBI Description

The gene encodes a small, highly conserved cytoplasmic protein that bind long-chain fatty acids and other hydrophobic ligands. The encoded protein is important in the establishment of the radial glial fiber in the developing brain. Alternative splicing and promoter usage results in multiple transcript variants encoding different isoforms. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Jan 2016]

Uniprot Description

FABP7: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Cell cycle regulation; Cell development/differentiation; Lipid-binding

Chromosomal Location of Human Ortholog: 6q22.31

Cellular Component: cytoplasm; cytosol; nucleoplasm

Biological Process: negative regulation of cell proliferation; nervous system development; triacylglycerol catabolic process

Research Articles on BLBP / FABP7

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Product Notes

The BLBP / FABP7 fabp7 (Catalog #AAA2545483) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The recombinant human FABP7 consists of 132 amino acids and predicts a molecular mass of 14.9 KDa. It migrates as an approximately 16 KDa band in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the BLBP / FABP7 fabp7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BLBP / FABP7, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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