Proteinase-activated receptor 1 (F2r) Recombinant Protein | F2r recombinant protein
Recombinant Rat Proteinase-activated receptor 1 (F2r)
NCBI and Uniprot Product Information
NCBI Description
plays a role in blood coagulation, inflammatory response, and cell proliferation; mediates signal transduction via MAP kinase and other signaling pathways [RGD, Feb 2006]
Uniprot Description
PAR1: a G-protein coupled high-affinity receptor for activated thrombin or trypsin. Coupled to G proteins that stimulate phosphoinositide hydrolysis. Coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelet activation and in vascular development.
Protein type: Cell development/differentiation; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR
Cellular Component: postsynaptic membrane; cell; early endosome; integral to membrane; plasma membrane; caveola; neuromuscular junction; cytosol
Molecular Function: G-protein coupled receptor activity; G-protein alpha-subunit binding; G-protein beta-subunit binding; receptor binding; thrombin receptor activity
Biological Process: elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of blood coagulation; activation of MAPKK activity; negative regulation of glomerular filtration; positive regulation of transcription, DNA-dependent; positive regulation of collagen biosynthetic process; positive regulation of JAK-STAT cascade; positive regulation of caspase activity; response to lipopolysaccharide; negative regulation of cell proliferation; connective tissue replacement during inflammatory response; elevation of cytosolic calcium ion concentration; positive regulation of MAPKKK cascade; regulation of interleukin-1 beta production; positive regulation of cell proliferation; protein kinase C activation; response to wounding; negative regulation of neuron apoptosis; positive regulation of smooth muscle contraction; establishment of synaptic specificity at neuromuscular junction; inflammatory response; STAT protein nuclear translocation; caspase activation; platelet activation; positive regulation of I-kappaB kinase/NF-kappaB cascade; death; positive regulation of Rho protein signal transduction; positive regulation of phosphoinositide 3-kinase cascade; G-protein coupled receptor protein signaling pathway; tyrosine phosphorylation of STAT protein; homeostasis of number of cells within a tissue; release of sequestered calcium ion into cytosol; regulation of blood coagulation; positive regulation of vasoconstriction; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); regulation of sensory perception of pain; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of calcium ion transport; blood coagulation; positive regulation of cell migration
Research Articles on F2r
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Product Notes
The F2r f2r (Catalog #AAA952694) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 46-432. The amino acid sequence is listed below: SFFLRNPSED TFEQFPLGDE EEKNESIPLE GRAVYLNKSR FPPMPPPPFI SEDASGYLTS PWLTLFIPSV YTFVFIVSLP LNILAIAVFV FRMKVKKPAV VYMLHLAMAD VLFVSVLPFK ISYYFSGTDW QFGSGMCRFA TAACYCNMYA SIMLMTVISI DRFLAVVYPI QSLSWRTLGR ANFTCVVIWV MAIMGVVPLL LKEQTTQVPG LNITTCHDVL NETLLHGFYS YYFSAFSAIF FLVPLIISTV CYTSIIRCLS SSAVANRSKK SRALFLSAAV FCIFIVCFGP TNVLLIVHYL LLSDSPGTET AYFAYLLCVC VTSVASCIDP LIYYYASSEC QKHLYSILCC RESSDSNSCN STGQLMPSKM DTCSSHLNNS IYKKLLA. It is sometimes possible for the material contained within the vial of "Proteinase-activated receptor 1 (F2r), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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