Rat Estrogen receptor ELISA Kit | Esr1 elisa kit
Rat Estrogen receptor ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
acts as a transcriptional activator when bound to estrogen; may play a role in myocardial regulation [RGD, Feb 2006]
Uniprot Description
ER-alpha: a nuclear hormone receptor and transcription factor. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Two splice-variant isoforms have been described.
Protein type: DNA-binding; Nuclear receptor
Cellular Component: cytoplasm; cytosol; Golgi apparatus; mitochondrion; neuron projection; nuclear chromatin; nucleus; perikaryon; perinuclear region of cytoplasm; plasma membrane; protein complex; T-tubule; terminal button
Molecular Function: ATPase binding; beta-catenin binding; chromatin binding; DNA binding; enzyme binding; estrogen receptor activity; estrogen response element binding; hormone binding; identical protein binding; ligand-dependent nuclear receptor activity; protein binding; protein complex binding; sequence-specific DNA binding; steroid binding; steroid hormone receptor activity; transcription factor activity; transcription factor binding; type 1 metabotropic glutamate receptor binding; zinc ion binding
Biological Process: androgen metabolic process; antral ovarian follicle growth; decidualization; elevation of cytosolic calcium ion concentration; epithelial cell development; estrogen receptor signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); male gonad development; negative regulation of glucose import; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of smooth muscle cell proliferation; negative regulation of transcription factor activity; osteoblast development; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of epithelial cell proliferation; positive regulation of fibroblast proliferation; positive regulation of nitric oxide biosynthetic process; positive regulation of nitric-oxide synthase activity; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of apoptosis; regulation of neuron apoptosis; regulation of transcription, DNA-dependent; response to estradiol stimulus; response to estrogen stimulus; Sertoli cell development; Sertoli cell proliferation; steroid hormone mediated signaling; steroid hormone receptor signaling pathway; transcription from RNA polymerase II promoter; transcription, DNA-dependent; uterus development; vagina development
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Product Notes
The Rat Esr1 esr1 (Catalog #AAA2880749) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2880749 ELISA Kit recognizes Rat Esr1. It is sometimes possible for the material contained within the vial of "Estrogen receptor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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