Endoplasmic Reticulum Resident Protein 27 Recombinant Protein | ERP27 recombinant protein

Recombinant Human Endoplasmic Reticulum Resident Protein 27

Cat. Num. AAA2556608

• Gene Names: ERP27; PDIA8; C12orf46
• Purity: >95% as determined by reducing SDS-PAGE.
• Synonyms: Endoplasmic Reticulum Resident Protein 27; Recombinant Human Endoplasmic Reticulum Resident Protein 27; ER Protein 27; ERp27; ERP27; C12orf46; ERP27 recombinant protein

• Host: Human Cells
• Purity/Purification: >95% as determined by reducing SDS-PAGE.
• Form/Format: Lyophilized from a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
• Sequence Length: 172

• Species: Human
• Endotoxin: <1.0 EU per ug as determined by LAL test.
• Fragment: Glu26-Leu273
• Fusion Tag: C-6His
• Preparation and Storage: Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.; Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days.; Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.

SDS-Page

Related Product Information for ERP27 recombinant protein

Protein Construction: Recombinant Human Endoplasmic Reticulum Resident Protein 27 is produced by our Mammalian expression system and the target gene encoding Glu26-Leu273 is expressed with a 6His tag at the C-terminus.

Background: Endoplasmic reticulum resident protein 27, also known as ER protein 27, C12orf46 and ERP27, is an endoplasmic reticulum luminal protein which is a member of the protein disulfide isomerase family. ERP27 contains one thioredoxin domain and does not contain a CXXC active site motif. ERP27 is widely expressed in many tissues; it has highest expression in pancreas, with lower levels in spleen, lung, kidney, thymus, and bone marrow. ERP27 interacts with PDIA3 and binds somatostatin-14 via hydrophobic interactions. ERP27 may act as a protease, protein disulfide isomerase, thiol-disulfide oxidase or phospholipase.

NCBI and Uniprot Product Information

• NCBI GI #: 663854316
• NCBI GeneID: 121506
• NCBI Accession #: NP_001287713.1
• NCBI GenBank Nucleotide #: NM_001300784.1
• UniProt Accession #: Q96DN0
• Molecular Weight: Molecular Mass: 28.8kDa; Actual Protein Molecular Mass: 36kDa
• NCBI Official Full Name: endoplasmic reticulum resident protein 27 isoform 2
• NCBI Official Synonym Full Names: endoplasmic reticulum protein 27
• NCBI Official Symbol: ERP27
• NCBI Official Synonym Symbols: PDIA8; C12orf46
• NCBI Protein Information: endoplasmic reticulum resident protein 27
• UniProt Protein Name: Endoplasmic reticulum resident protein 27
• Protein Family: Endoplasmic reticulum resident protein
• UniProt Gene Name: ERP27
• UniProt Synonym Gene Names: C12orf46; ER protein 27; ERp27

NCBI Description

This gene encodes a noncatalytic member of the protein disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins. The canonical protein has an N-terminal signal sequence, two thioredoxin (TRX)-like domains and a C-terminal ER-retention sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which lack domains present in the canonical protein. [provided by RefSeq, Dec 2016]

Uniprot Description

MiscellaneousDoes not contain a CXXC active site motif indicating that it is a catalytically redox-inactive member of the protein disulfide isomerase family.