Activity
(Specific Activity: Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.)
EPHA7 recombinant protein
EPHA7, Active
Gene Names
Epha7; Ebk; Ehk3; Mdk1; Cek11; Hek11
Applications
Western Blot
Synonyms
EPHA7; Active; CEK11; EHK3; HEK11; MDK1; EPHA7 recombinant protein
Host
Sf9 insect cells
Form/Format
Recombinant protein stored in 50mM Tris-HCl, pH7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Applicable Applications for EPHA7 recombinant protein
Kinase Assay, Western Blot (WB)
Tag
GST
Species
Mouse
Preparation and Storage
Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Activity
(Specific Activity: Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.)
Activity
(Specific Activity: Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.)
SDS-Page
(Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.)
SDS-Page
(Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.)
Related Product Information for EPHA7 recombinant protein
Recombinant mouse EPHA7 (580-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The EPHA7 gene accession number is BC026153.
EPHA7 is a member of the ephrin receptor subfamily of protein-tyrosine kinases family that have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EpHsubfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2-fibronectin types III repeats. EPHA7 mediated signaling act as a physiologic trigger for apoptosis that can alter brain size and shape by regulating the number of neural progenitors (1). The high expression of EPHA7 protein plays an important role in the malignancy transformation, invasion progression and metastasis of primary hepatocellular carcinoma (2).
EPHA7 is a member of the ephrin receptor subfamily of protein-tyrosine kinases family that have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EpHsubfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2-fibronectin types III repeats. EPHA7 mediated signaling act as a physiologic trigger for apoptosis that can alter brain size and shape by regulating the number of neural progenitors (1). The high expression of EPHA7 protein plays an important role in the malignancy transformation, invasion progression and metastasis of primary hepatocellular carcinoma (2).
Product Categories/Family for EPHA7 recombinant protein
References
1. Depaepe, V. et.al: Ephrin signalling controls brain size by regulating apoptosis of neural progenitors. Nature 435: 1244-1250, 2005.
2. Zhang SJ. et.al: Expression of EphA7 protein in primary hepatocellular carcinoma and its clinical significance. Zhonghua Wai Ke Za Zhi. 2010 Jan 1;48(1):53-6.
2. Zhang SJ. et.al: Expression of EphA7 protein in primary hepatocellular carcinoma and its clinical significance. Zhonghua Wai Ke Za Zhi. 2010 Jan 1;48(1):53-6.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
73.0 kDa
NCBI Official Full Name
Mus musculus Eph receptor A7, mRNA
NCBI Official Synonym Full Names
Eph receptor A7
NCBI Official Symbol
Epha7
NCBI Official Synonym Symbols
Ebk; Ehk3; Mdk1; Cek11; Hek11
NCBI Protein Information
ephrin type-A receptor 7
Protein Family
Research Articles on EPHA7
Similar Products
Product Notes
The EPHA7 (Catalog #AAA516913) is a Recombinant Protein produced from Sf9 insect cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's EPHA7 can be used in a range of immunoassay formats including, but not limited to, Kinase Assay, Western Blot (WB). Researchers should empirically determine the suitability of the EPHA7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EPHA7, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
